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Dextrose Side Effects

The most commonly reported side effects of dextrose include death, peritonitis, and hypotension, based on 137,531 FDA adverse event reports from 2004 to 2025.

Dextrose side effects

Percentages show how often each reaction appears relative to total reports for dextrose.

1
Death10.3%14,151
2
Peritonitis4.9%6,691
3
Hypotension3.8%5,232
4
Peritonitis Bacterial3.5%4,830
5
Peritoneal Dialysis Complication2.9%4,024
6
Fluid Overload2.8%3,919
7
Death2.7%3,703
8
Dehydration2.4%3,341
9
Pneumonia2.2%3,047
10
Vomiting2.0%2,686
11
Infection1.9%2,676
12
Dyspnoea1.9%2,657
13
Hypertension1.9%2,597
14
Abdominal Distension1.9%2,579
15
Malaise1.8%2,457

These are voluntary reports and do not establish that dextrose caused these reactions.

Report severity

78.9%Serious108,564 reports
46.0%Hospitalizations63,306 reports
27.2%Fatal37,451 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dextrose drug interactions

Other drugs that appear in adverse event reports alongside dextrose. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-chloride30.8%42,302
2
Calcium-chloride29.8%40,957
3
Magnesium-chloride29.5%40,513
4
Sodium-lactate29.1%40,003
5
Icodextrin13.2%18,214
6
Potassium-chloride1.0%1,383
7
Cyclophosphamide0.8%1,110
8
Carboplatin0.7%998
9
Oxaliplatin0.7%977
10
Sodium-bicarbonate0.7%911
11
Magnesium-sulfate0.6%846
12
Heparin0.5%716
13
Amino-acids0.5%713
14
Paclitaxel0.5%691
15
Insulin0.5%650

Taken alongside

1
Sodium-chloride4.3%5,958
2
Insulin2.7%3,763
3
Acetaminophen2.7%3,712
4
Potassium-chloride2.5%3,490
5
Furosemide2.4%3,268
6
Aspirin1.9%2,614
7
Amlodipine1.6%2,226
8
Ondansetron1.6%2,215
9
Atorvastatin-calcium1.5%2,079
10
Omeprazole1.5%2,042
11
Heparin1.5%2,027
12
Metoprolol1.3%1,765
13
Pantoprazole-sodium1.3%1,726
14
Folic-acid1.2%1,642
15
Calcium-chloride1.2%1,587

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dextrose side effects

43.7% of dextrose adverse event reports involve female patients and 50.1% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.7%
Male50.1%
Unknown6.2%

Age group

< 21.5%
2–111.8%
12–171.3%
18–6453.5%
65+41.9%

What is dextrose used for

Conditions and purposes for which patients were taking dextrose when the adverse event was reported.

Abdominal DistensionAbdominal PainAccidental ExposureAccidental Exposure To ProductAcid Base BalanceAcidosisAcneAcquired Cystic Kidney DiseaseAcute Kidney InjuryAcute Lymphocytic LeukaemiaAcute Myeloid LeukaemiaAcute Respiratory FailureAdenocarcinomaAdenovirus InfectionAdjuvant Therapy

Showing 15 of 1,013 indications

Dextrose brand names and reporting trend

Dextrose is sold under the brand name Dextrose 70% In Plastic Container.

Brand names

Dextrose 70% In Plastic Container166,517

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dextrose with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.