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Dexpanthenol Side Effects

The most commonly reported side effects of dexpanthenol include flushing, pruritus, and nausea, based on 5,925 FDA adverse event reports from 2004 to 2025.

Dexpanthenol side effects

Percentages show how often each reaction appears relative to total reports for dexpanthenol.

1
Flushing12.2%721
2
Pruritus4.8%284
3
Nausea4.5%264
4
Off Label Use4.2%246
5
Nausea3.6%213
6
Diarrhoea3.6%211
7
Feeling Hot3.4%201
8
Paraesthesia3.4%200
9
Gastrooesophageal Reflux Disease3.3%194
10
Somnolence3.2%188
11
Fatigue3.1%183
12
Dizziness2.9%169
13
Dyspnoea2.8%164
14
Dyspnoea2.7%162
15
Fatigue2.7%162

These are voluntary reports and do not establish that dexpanthenol caused these reactions.

Report severity

61.8%Serious3,663 reports
40.0%Hospitalizations2,368 reports
9.4%Fatal554 reports

Seriousness is determined by the reporter, not by OpenClaim.

Dexpanthenol drug interactions

Other drugs that appear in adverse event reports alongside dexpanthenol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Niacin14.5%862
2
Adalimumab8.4%499
3
Ascorbic-acid8.3%489
4
Pyridoxine6.9%406
5
Folic-acid6.8%404
6
Warfarin6.2%366
7
Cyanocobalamin5.6%333
8
Riboflavin5.2%311
9
Ergocalciferol5.1%301
10
Prednisone5.1%301
11
Cholecalciferol5.0%296
12
Thiamine5.0%294
13
Hydromorphone-hydrochloride4.6%270
14
Biotin4.4%262
15
Calcium-carbonate4.4%262

Taken alongside

1
Ergocalciferol73.8%4,374
2
Folic-acid73.4%4,348
3
Ascorbic-acid73.0%4,323
4
Riboflavin72.7%4,308
5
Thiamine72.3%4,284
6
Cyanocobalamin71.9%4,258
7
Pyridoxine71.7%4,248
8
Biotin70.6%4,181
9
Niacinamide70.4%4,172
10
Vitamin-e70.0%4,149
11
Vitamin-a69.5%4,116
12
Aspirin27.0%1,601
13
Acetaminophen15.4%911
14
Calcium13.4%791
15
Fish12.3%727

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports dexpanthenol side effects

53.4% of dexpanthenol adverse event reports involve female patients and 41.2% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female53.4%
Male41.2%
Unknown5.4%

Age group

< 21.0%
2–111.1%
12–170.9%
18–6450.5%
65+46.4%

What is dexpanthenol used for

Conditions and purposes for which patients were taking dexpanthenol when the adverse event was reported.

Abdominal Pain UpperAccidental ExposureAcneAnaemiaAnal FissureAnal PruritusAndrogenetic AlopeciaAntiinflammatory TherapyAphthous StomatitisAstheniaAdverse EventAlopeciaAndrogenetic AlopeciaAntacid TherapyAquagenic Wrinkling Of Palms

Showing 15 of 208 indications

Dexpanthenol brand names and reporting trend

Dexpanthenol is sold under the brand name M.v.i.-12 Adult.

Brand names

M.v.i.-12 Adult1,792

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking dexpanthenol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.