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Desoxyribonuclease Side Effects

The most commonly reported side effects of desoxyribonuclease include stomatitis, white blood cell count decreased, and vomiting, based on 24 FDA adverse event reports from 2004 to 2025.

Desoxyribonuclease side effects

Percentages show how often each reaction appears relative to total reports for desoxyribonuclease.

1
Stomatitis12.5%3
2
White Blood Cell Count Decreased8.3%2
3
Vomiting8.3%2
4
Diarrhoea8.3%2
5
Mucous Membrane Disorder8.3%2
6
Encephalitis Fungal8.3%2
7
Haematocrit Decreased4.2%1
8
Haemoglobin Decreased4.2%1
9
Red Blood Cell Count Decreased4.2%1
10
Acne4.2%1
11
Blood Pressure Decreased4.2%1
12
Dehydration4.2%1
13
Drug Effect Decreased4.2%1
14
Dry Skin4.2%1
15
Dyspepsia4.2%1

These are voluntary reports and do not establish that desoxyribonuclease caused these reactions.

Report severity

87.5%Serious21 reports
54.2%Hospitalizations13 reports
12.5%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Desoxyribonuclease drug interactions

Other drugs that appear in adverse event reports alongside desoxyribonuclease. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Melphalan25.0%6
2
Fludarabine-phosphate20.8%5
3
Fentanyl8.3%2
4
Fluorouracil8.3%2
5
Fluconazole8.3%2
6
Ivacaftor8.3%2
7
Docetaxel4.2%1
8
Gefitinib4.2%1
9
Arsenic-trioxide4.2%1
10
Doxorubicin-hydrochloride4.2%1
11
Acyclovir4.2%1
12
Tacrolimus4.2%1
13
Piperacillin4.2%1
14
Meropenem4.2%1
15
Methotrexate4.2%1

Taken alongside

1
Chloramphenicol58.3%14
2
Fibrinolysin58.3%14
3
Lidocaine33.3%8
4
Apomorphine-hydrochloride20.8%5
5
Methotrexate20.8%5
6
Hydrocortisone16.7%4
7
Granisetron16.7%4
8
Sodium-bicarbonate16.7%4
9
Acyclovir16.7%4
10
Ursodiol16.7%4
11
Aspirin16.7%4
12
Albuterol16.7%4
13
Allopurinol12.5%3
14
Meropenem12.5%3
15
Cyclosporine12.5%3

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports desoxyribonuclease side effects

45.8% of desoxyribonuclease adverse event reports involve female patients and 50.0% involve male patients. The largest age group is adult at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female45.8%
Male50.0%
Unknown4.2%

Age group

< 20.0%
2–1114.3%
12–177.1%
18–6450.0%
65+28.6%

What is desoxyribonuclease used for

Conditions and purposes for which patients were taking desoxyribonuclease when the adverse event was reported.

Cellulitis OrbitalDrug Use For Unknown IndicationOsteoporosisProduct Used For Unknown IndicationProphylaxisStomatitis

Desoxyribonuclease brand names and reporting trend

Desoxyribonuclease is sold under the brand name Elase-chloromycetin.

Brand names

Elase-chloromycetin11

Quarterly reports (20042025)

200420202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking desoxyribonuclease with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.