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Desoximetasone Side Effects

The most commonly reported side effects of desoximetasone include pain, fatigue, and alopecia, based on 18,467 FDA adverse event reports from 2004 to 2025. 53.1% of reports found the drug to be ineffective.

Desoximetasone side effects

Percentages show how often each reaction appears relative to total reports for desoximetasone.

1
Drug Ineffective53.1%9,811
2
Pain47.8%8,825
3
Fatigue46.8%8,651
4
Alopecia44.0%8,130
5
Rheumatoid Arthritis43.7%8,070
6
Systemic Lupus Erythematosus43.2%7,970
7
Pemphigus42.0%7,747
8
Abdominal Discomfort41.7%7,703
9
Glossodynia40.7%7,515
10
Swelling38.2%7,049
11
Hand Deformity36.9%6,821
12
Rash36.5%6,739
13
Arthropathy36.2%6,687
14
Drug Intolerance35.5%6,551
15
Synovitis34.5%6,375

These are voluntary reports and do not establish that desoximetasone caused these reactions.

Report severity

94.6%Serious17,465 reports
36.0%Hospitalizations6,639 reports
24.6%Fatal4,546 reports

Seriousness is determined by the reporter, not by OpenClaim.

Desoximetasone drug interactions

Other drugs that appear in adverse event reports alongside desoximetasone. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Methotrexate68.8%12,705
2
Abatacept64.9%11,992
3
Etanercept64.2%11,862
4
Adalimumab63.7%11,766
5
Infliximab62.3%11,497
6
Leflunomide61.7%11,401
7
Hydroxychloroquine-sulfate60.3%11,133
8
Tocilizumab59.9%11,061
9
Prednisone58.8%10,855
10
Rituximab57.8%10,671
11
Sulfasalazine56.5%10,442
12
Folic-acid55.5%10,248
13
Certolizumab-pegol55.5%10,240
14
Golimumab54.6%10,077
15
Cetirizine-hydrochloride53.4%9,863

Taken alongside

1
Acetaminophen27.1%5,010
2
Pantoprazole-sodium24.9%4,607
3
Sulfasalazine24.6%4,541
4
Ibuprofen22.4%4,137
5
Tofacitinib17.7%3,265
6
Ergocalciferol16.1%2,980
7
Prednisone15.6%2,879
8
Desogestrel13.9%2,563
9
Ethinyl-estradiol13.7%2,528
10
Quetiapine-fumarate12.9%2,386
11
Lisinopril12.7%2,337
12
Diclofenac12.4%2,292
13
Lorazepam12.3%2,280
14
Ramipril12.2%2,261
15
Caffeine11.9%2,193

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports desoximetasone side effects

74.4% of desoximetasone adverse event reports involve female patients and 9.8% involve male patients. The largest age group is adult at 83%. These figures reflect who reports side effects, not underlying risk.

Sex

Female74.4%
Male9.8%
Unknown15.8%

Age group

< 20.7%
2–110.4%
12–170.6%
18–6482.9%
65+15.4%

What is desoximetasone used for

Conditions and purposes for which patients were taking desoximetasone when the adverse event was reported.

Abdominal PainAcneAdverse EventAlopeciaAlopecia AreataAnhidrosisAnkylosing SpondylitisArthralgiaArthritisArthropathyArthropod BiteAcneAdrenal InsufficiencyAphthous UlcerArthralgia

Showing 15 of 211 indications

Desoximetasone brand names and reporting trend

Desoximetasone is sold under the brand name Topicort Lp.

Brand names

Topicort Lp55,969

Quarterly reports (20042025)

20042010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking desoximetasone with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.