OpenClaim

Desonide Side Effects

The most commonly reported side effects of desonide include macular degeneration, off label use, and nausea, based on 5,507 FDA adverse event reports from 2004 to 2025. 21.7% of reports found the drug to be ineffective.

Desonide side effects

Percentages show how often each reaction appears relative to total reports for desonide.

1
Drug Ineffective21.7%1,196
2
Macular Degeneration14.1%775
3
Off Label Use7.7%425
4
Nausea7.1%389
5
Pain7.0%387
6
Headache6.1%336
7
Rash6.0%330
8
Erythema5.9%323
9
Pruritus5.8%319
10
Pyrexia5.7%312
11
Psoriasis5.4%297
12
Malaise5.2%288
13
Weight Decreased5.1%279
14
Therapeutic Product Effect Incomplete4.7%259
15
Abdominal Pain4.1%226

These are voluntary reports and do not establish that desonide caused these reactions.

Report severity

56.0%Serious3,084 reports
23.3%Hospitalizations1,284 reports
4.3%Fatal238 reports

Seriousness is determined by the reporter, not by OpenClaim.

Desonide drug interactions

Other drugs that appear in adverse event reports alongside desonide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Adalimumab17.1%942
2
Triamcinolone16.1%886
3
Dupilumab15.4%850
4
Betamethasone15.2%835
5
Prednisone14.8%814
6
Metronidazole14.0%769
7
Acetaminophen13.9%768
8
Clarithromycin13.9%767
9
Fluticasone13.9%766
10
Alprazolam13.9%763
11
Diphenhydramine13.8%762
12
Azithromycin13.8%762
13
Budesonide13.8%761
14
Mupirocin13.7%757
15
Nicotine13.7%757

Taken alongside

1
Triamcinolone16.7%918
2
Acetaminophen16.3%900
3
Ergocalciferol16.1%889
4
Clobetasol-propionate15.9%877
5
Albuterol14.4%792
6
Fluticasone13.9%766
7
Valsartan11.9%656
8
Aspirin11.8%648
9
Levothyroxine-sodium10.4%570
10
Prednisone10.4%570
11
Omeprazole10.1%557
12
Atorvastatin-calcium9.3%511
13
Gabapentin9.1%499
14
Cetirizine-hydrochloride8.9%492
15
Ketoconazole8.4%463

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports desonide side effects

58.2% of desonide adverse event reports involve female patients and 34.1% involve male patients. The largest age group is adult at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female58.2%
Male34.1%
Unknown7.8%

Age group

< 21.2%
2–116.4%
12–174.7%
18–6454.6%
65+33.1%

What is desonide used for

Conditions and purposes for which patients were taking desonide when the adverse event was reported.

AcarodermatitisAccidental Exposure To ProductAcneActinic CheilitisActinic KeratosisAdverse EventAllergy To AnimalAllergy To Arthropod BiteAllergy To ChemicalsAlopeciaAlopecia AreataAnal PruritusAntibiotic TherapyAntifungal TreatmentArthritis

Showing 15 of 231 indications

Desonide brand names and reporting trend

Desonide is sold under the brand name Verdeso.

Brand names

Verdeso5,240

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking desonide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.