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Deoxycholic Side Effects

The most commonly reported side effects of deoxycholic include off label use, injection site swelling, and pyrexia, based on 7,952 FDA adverse event reports from 2004 to 2025. 6.7% of reports found the drug to be ineffective.

Deoxycholic side effects

Percentages show how often each reaction appears relative to total reports for deoxycholic.

1
Off Label Use8.6%687
2
Drug Ineffective6.7%532
3
Injection Site Swelling3.8%306
4
Pyrexia3.8%304
5
Swelling3.4%268
6
Diarrhoea2.9%231
7
Injection Site Pain2.5%197
8
Hepatic Function Abnormal2.3%185
9
Nausea2.3%181
10
Condition Aggravated2.3%179
11
Pneumonia2.2%177
12
Anaemia2.2%174
13
Decreased Appetite2.1%167
14
Platelet Count Decreased1.9%151
15
Vomiting1.9%149

These are voluntary reports and do not establish that deoxycholic caused these reactions.

Report severity

71.0%Serious5,642 reports
34.7%Hospitalizations2,757 reports
14.9%Fatal1,183 reports

Seriousness is determined by the reporter, not by OpenClaim.

Deoxycholic drug interactions

Other drugs that appear in adverse event reports alongside deoxycholic. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tacrolimus4.0%315
2
Mycophenolate3.5%281
3
Cyclophosphamide3.2%256
4
Fludarabine-phosphate3.1%246
5
Busulfan2.8%225
6
Cyclosporine2.8%223
7
Methotrexate2.6%207
8
Prednisolone2.3%182
9
Furosemide2.0%158
10
Defibrotide-sodium1.9%152
11
Ribavirin1.8%143
12
Prednisone1.6%129
13
Melphalan1.4%110
14
Azathioprine1.4%110
15
Methylprednisolone1.2%99

Taken alongside

1
Furosemide9.4%744
2
Amlodipine6.8%540
3
Omeprazole6.3%499
4
Lansoprazole5.4%432
5
Acetaminophen5.2%417
6
Prednisolone4.9%388
7
Spironolactone4.8%381
8
Aspirin4.1%330
9
Methylprednisolone4.1%323
10
Insulin3.9%312
11
Fluconazole3.8%304
12
Famotidine3.8%301
13
Sulfamethoxazole3.8%299
14
Esomeprazole3.7%291
15
Tacrolimus3.6%285

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports deoxycholic side effects

48.8% of deoxycholic adverse event reports involve female patients and 33.6% involve male patients. The largest age group is adult at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female48.8%
Male33.6%
Unknown17.6%

Age group

< 23.2%
2–115.8%
12–174.1%
18–6455.2%
65+31.7%

What is deoxycholic used for

Conditions and purposes for which patients were taking deoxycholic when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAbdominal Pain UpperAccidental Exposure To ProductAcute Graft Versus Host DiseaseAcute Kidney InjuryAcute Lymphocytic LeukaemiaAcute Lymphocytic Leukaemia RecurrentAcute Myeloid LeukaemiaAcute Myelomonocytic LeukaemiaAdverse EventAlagille SyndromeAlanine Aminotransferase IncreasedAlcoholic Liver DiseaseAmyloidosis

Showing 15 of 298 indications

Deoxycholic brand names and reporting trend

Deoxycholic is sold under the brand name Kybella.

Brand names

Kybella6,143

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking deoxycholic with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.