OpenClaim

Delafloxacin Side Effects

The most commonly reported side effects of delafloxacin include diarrhoea, off label use, and nausea, based on 263 FDA adverse event reports from 2018 to 2025. 4.2% of reports found the drug to be ineffective.

Delafloxacin side effects

Percentages show how often each reaction appears relative to total reports for delafloxacin.

1
Diarrhoea30.0%79
2
Off Label Use11.4%30
3
Nausea8.4%22
4
Malaise5.7%15
5
Arthralgia5.3%14
6
Decreased Appetite5.3%14
7
Rash4.9%13
8
Drug Ineffective4.2%11
9
Product Use In Unapproved Indication3.8%10
10
Pain3.8%10
11
Drug Effective For Unapproved Indication3.8%10
12
Tremor3.8%10
13
Vomiting3.4%9
14
Abdominal Discomfort3.4%9
15
Pallor3.4%9

These are voluntary reports and do not establish that delafloxacin caused these reactions.

Report severity

33.1%Serious87 reports
11.8%Hospitalizations31 reports
3.4%Fatal9 reports

Seriousness is determined by the reporter, not by OpenClaim.

Delafloxacin drug interactions

Other drugs that appear in adverse event reports alongside delafloxacin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Atorvastatin-calcium3.4%9
2
Clonazepam1.1%3
3
Fulvestrant1.1%3
4
Hydroxyzine1.1%3
5
Ribociclib1.1%3
6
Ganciclovir1.1%3
7
Dupilumab0.8%2
8
Hydroxychloroquine-sulfate0.8%2
9
Prednisone0.8%2
10
Dornase-alfa0.4%1
11
Ivacaftor0.4%1
12
Methadone-hydrochloride0.4%1
13
Tobramycin0.4%1
14
Metronidazole0.4%1
15
Eravacycline-dihydrochloride0.4%1

Taken alongside

1
Atorvastatin-calcium9.5%25
2
Furosemide9.5%25
3
Insulin9.1%24
4
Metformin9.1%24
5
Aspirin8.7%23
6
Lisinopril8.7%23
7
Omeprazole8.0%21
8
Gabapentin7.6%20
9
Levothyroxine-sodium7.2%19
10
Ergocalciferol7.2%19
11
Metoprolol6.1%16
12
Acetaminophen6.1%16
13
Ciprofloxacin6.1%16
14
Losartan-potassium4.9%13
15
Vancomycin4.6%12

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports delafloxacin side effects

44.5% of delafloxacin adverse event reports involve female patients and 42.6% involve male patients. The largest age group is adult at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.5%
Male42.6%
Unknown12.9%

Age group

< 20.0%
2–111.1%
12–170.0%
18–6454.5%
65+44.3%

What is delafloxacin used for

Conditions and purposes for which patients were taking delafloxacin when the adverse event was reported.

AbscessAntibiotic ProphylaxisAmputationArthritis BacterialBacteraemiaBacterial InfectionBeta Haemolytic Streptococcal InfectionCellulitisChronic SinusitisCoughCampylobacter InfectionCellulitisCellulitis StaphylococcalComputerised Tomogram ThoraxDevice Related Infection

Showing 15 of 63 indications

Delafloxacin brand names and reporting trend

Delafloxacin is sold under the brand name Baxdela.

Brand names

Baxdela53

Quarterly reports (20182025)

2018202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking delafloxacin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.