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Deferoxamine Side Effects

The most commonly reported side effects of deferoxamine include off label use, pyrexia, and serum ferritin increased, based on 2,763 FDA adverse event reports from 2004 to 2025. 4.9% of reports found the drug to be ineffective.

Deferoxamine side effects

Percentages show how often each reaction appears relative to total reports for deferoxamine.

1
Drug Ineffective4.9%136
2
Off Label Use4.9%136
3
Pyrexia4.6%126
4
Serum Ferritin Increased4.5%124
5
Death4.0%111
6
Diarrhoea3.9%109
7
Fatigue3.6%99
8
Haemoglobin Decreased3.5%96
9
Dyspnoea3.4%94
10
Vomiting3.4%93
11
Nausea3.2%88
12
Abdominal Pain2.8%76
13
Pneumonia2.6%73
14
Anaemia2.6%72
15
Headache2.5%70

These are voluntary reports and do not establish that deferoxamine caused these reactions.

Report severity

89.8%Serious2,480 reports
41.7%Hospitalizations1,152 reports
17.9%Fatal494 reports

Seriousness is determined by the reporter, not by OpenClaim.

Deferoxamine drug interactions

Other drugs that appear in adverse event reports alongside deferoxamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Deferasirox17.1%472
2
Deferiprone11.3%311
3
Eculizumab3.0%83
4
Cyclosporine2.9%79
5
Sodium-chloride2.1%57
6
Busulfan1.8%51
7
Tacrolimus1.8%50
8
Adalimumab1.7%47
9
Lenalidomide1.7%46
10
Sterile1.7%46
11
Fluconazole1.6%45
12
Methotrexate1.6%45
13
Fludarabine-phosphate1.6%44
14
Azacitidine1.5%42
15
Ibuprofen1.5%42

Taken alongside

1
Folic-acid9.9%274
2
Ergocalciferol5.2%145
3
Acetaminophen5.2%145
4
Furosemide5.2%144
5
Aspirin5.0%138
6
Pantoprazole-sodium4.4%121
7
Deferasirox4.3%119
8
Omeprazole4.1%114
9
Metoprolol4.1%112
10
Insulin3.7%103
11
Levothyroxine-sodium3.4%94
12
Prednisone3.1%87
13
Allopurinol2.7%75
14
Simvastatin2.6%72
15
Ondansetron2.5%69

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports deferoxamine side effects

51.9% of deferoxamine adverse event reports involve female patients and 38.1% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female51.9%
Male38.1%
Unknown10.0%

Age group

< 23.0%
2–117.6%
12–177.4%
18–6453.7%
65+28.3%

What is deferoxamine used for

Conditions and purposes for which patients were taking deferoxamine when the adverse event was reported.

Acute Myeloid LeukaemiaAluminium OverloadAmyotrophic Lateral SclerosisAnaemiaAplasia Pure Red CellAplastic AnaemiaAtrial FibrillationAutismAutoimmune ThyroiditisAcute Hepatic FailureAllogenic Stem Cell TransplantationAnaemiaAplastic AnaemiaAtrial TachycardiaAutoimmune Thyroiditis

Showing 15 of 153 indications

Deferoxamine brand names and reporting trend

Deferoxamine is sold under the brand name Deferoxamine Mesylate.

Brand names

Deferoxamine Mesylate444

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking deferoxamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.