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Deferasirox Side Effects

The most commonly reported side effects of deferasirox include death, death, and diarrhoea, based on 26,755 FDA adverse event reports from 2005 to 2025.

Deferasirox side effects

Percentages show how often each reaction appears relative to total reports for deferasirox.

1
Death10.4%2,777
2
Death7.3%1,953
3
Diarrhoea5.1%1,369
4
Sickle Cell Anaemia With Crisis4.0%1,061
5
Diarrhoea3.8%1,021
6
Haemoglobin Decreased3.5%925
7
Pyrexia3.2%869
8
Serum Ferritin Increased3.2%851
9
Nausea3.2%846
10
Sickle Cell Anaemia With Crisis3.1%833
11
Malaise2.9%783
12
Pneumonia2.8%748
13
Fatigue2.7%715
14
Vomiting2.6%702
15
Pyrexia2.3%608

These are voluntary reports and do not establish that deferasirox caused these reactions.

Report severity

86.5%Serious23,149 reports
38.1%Hospitalizations10,196 reports
29.1%Fatal7,777 reports

Seriousness is determined by the reporter, not by OpenClaim.

Deferasirox drug interactions

Other drugs that appear in adverse event reports alongside deferasirox. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide2.5%656
2
Ruxolitinib2.1%565
3
Eculizumab1.8%470
4
Deferiprone1.6%440
5
Azacitidine1.6%415
6
Voxelotor1.4%386
7
Deferoxamine-mesylate1.3%341
8
Cyclosporine0.9%250
9
Venetoclax0.5%124
10
Eltrombopag0.5%122
11
L-glutamine0.4%120
12
Darbepoetin-alfa0.4%107
13
Hydroxyurea0.4%107
14
Luspatercept-aamt0.4%97
15
Filgrastim0.2%60

Taken alongside

1
Folic-acid8.2%2,199
2
Acetaminophen4.3%1,143
3
Furosemide3.9%1,056
4
Aspirin3.8%1,009
5
Hydroxyurea3.6%970
6
Ergocalciferol3.3%883
7
Levothyroxine-sodium2.9%764
8
Omeprazole2.8%737
9
Metoprolol2.4%648
10
Prednisone2.3%625
11
Oxycodone2.2%588
12
Allopurinol2.0%538
13
Pantoprazole-sodium2.0%531
14
Amlodipine1.8%487
15
Hydrocodone1.7%448

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports deferasirox side effects

44.8% of deferasirox adverse event reports involve female patients and 46.2% involve male patients. The largest age group is elderly at 43%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.8%
Male46.2%
Unknown9.1%

Age group

< 20.3%
2–118.5%
12–175.8%
18–6442.5%
65+42.9%

What is deferasirox used for

Conditions and purposes for which patients were taking deferasirox when the adverse event was reported.

5q Minus Syndrome5q Minus SyndromeAbdominal NeoplasmAbdominal Pain UpperAcute Biphenotypic LeukaemiaAcute LeukaemiaAcute Lymphocytic LeukaemiaAcute Lymphocytic Leukaemia (in Remission)Acute Lymphocytic Leukaemia RecurrentAcute Monocytic LeukaemiaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia (in Remission)Acute Myeloid LeukemiaAcute Myelomonocytic LeukaemiaAcute Promyelocytic Leukaemia

Showing 15 of 477 indications

Deferasirox brand names and reporting trend

Deferasirox is sold under the brand name Jadenu.

Brand names

Jadenu3,498

Quarterly reports (20052025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking deferasirox with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.