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Danicopan Side Effects

The most commonly reported side effects of danicopan include haemoglobin decreased, fatigue, and haemolysis, based on 190 FDA adverse event reports from 2024 to 2025. 4.7% of reports found the drug to be ineffective.

Danicopan side effects

Percentages show how often each reaction appears relative to total reports for danicopan.

1
Haemoglobin Decreased11.6%22
2
Fatigue9.5%18
3
Haemolysis8.9%17
4
Headache6.3%12
5
Extravascular Haemolysis6.3%12
6
Breakthrough Haemolysis5.3%10
7
Anaemia5.3%10
8
Drug Ineffective4.7%9
9
Pneumonia4.7%9
10
Off Label Use4.2%8
11
Blood Bilirubin Increased4.2%8
12
Platelet Count Decreased3.7%7
13
Asthenia3.2%6
14
Covid-192.6%5
15
Thrombocytopenia2.6%5

These are voluntary reports and do not establish that danicopan caused these reactions.

Report severity

67.9%Serious129 reports
21.6%Hospitalizations41 reports
5.3%Fatal10 reports

Seriousness is determined by the reporter, not by OpenClaim.

Danicopan drug interactions

Other drugs that appear in adverse event reports alongside danicopan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ravulizumab-cwvz73.7%140
2
Eculizumab9.5%18
3
Crovalimab-akkz2.1%4
4
Pegcetacoplan1.6%3
5
Prednisone0.5%1
6
Omeprazole0.5%1
7
Warfarin0.5%1
8
Rituximab0.5%1
9
Modafinil0.5%1
10
Cyclosporine0.5%1
11
Eltrombopag0.5%1

Taken alongside

1
Folic-acid7.9%15
2
Ergocalciferol4.2%8
3
Penicillin3.7%7
4
Cyanocobalamin3.2%6
5
Magnesium-oxide3.2%6
6
Aspirin3.2%6
7
Ondansetron3.2%6
8
Escitalopram-oxalate2.6%5
9
Levothyroxine-sodium2.6%5
10
Amlodipine2.6%5
11
Albuterol2.1%4
12
Rivaroxaban2.1%4
13
Furosemide2.1%4
14
Prednisolone2.1%4
15
Sertraline-hydrochloride2.1%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports danicopan side effects

53.7% of danicopan adverse event reports involve female patients and 33.7% involve male patients. The largest age group is elderly at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female53.7%
Male33.7%
Unknown12.6%

Age group

< 20.0%
2–110.0%
12–172.2%
18–6446.7%
65+51.1%

What is danicopan used for

Conditions and purposes for which patients were taking danicopan when the adverse event was reported.

Emphysematous PyelonephritisEssential ThrombocythaemiaExtravascular HaemolysisMyelodysplastic SyndromeParoxysmal Nocturnal HaemoglobinuriaProduct Used For Unknown IndicationVessel Harvesting

Danicopan brand names and reporting trend

Danicopan is sold under the brand name Voydeya.

Brand names

Voydeya83

Quarterly reports (20242025)

20242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking danicopan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.