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Daclizumab Side Effects

The most commonly reported side effects of daclizumab include alopecia, transplant dysfunction, and transplant rejection, based on 3,594 FDA adverse event reports from 2004 to 2025. 6.6% of reports found the drug to be ineffective.

Daclizumab side effects

Percentages show how often each reaction appears relative to total reports for daclizumab.

1
Alopecia12.4%444
2
Transplant Dysfunction11.5%415
3
Transplant Rejection10.7%386
4
Acne10.4%375
5
Ovarian Cyst10.2%368
6
Multiple Sclerosis Relapse8.8%317
7
Drug Ineffective6.6%237
8
Pain6.2%222
9
Pneumonia6.0%215
10
Condition Aggravated4.8%174
11
Liver Function Test Abnormal4.3%154
12
Rheumatoid Arthritis4.3%153
13
Fatigue4.0%142
14
Sleep Disorder Due To General Medical Condition, Insomnia Type4.0%142
15
Memory Impairment3.0%107

These are voluntary reports and do not establish that daclizumab caused these reactions.

Report severity

71.6%Serious2,575 reports
36.3%Hospitalizations1,305 reports
9.8%Fatal354 reports

Seriousness is determined by the reporter, not by OpenClaim.

Daclizumab drug interactions

Other drugs that appear in adverse event reports alongside daclizumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Mycophenolate32.2%1,159
2
Tacrolimus27.6%992
3
Cyclosporine19.2%691
4
Sirolimus17.6%633
5
Etanercept11.5%415
6
Infliximab11.2%403
7
Methylprednisolone9.3%336
8
Prednisone8.2%294
9
Prednisolone6.3%226
10
Sulfasalazine4.0%144
11
Dimethyl3.6%129
12
Dalfampridine3.5%124
13
Natalizumab3.3%117
14
Interferon2.1%74
15
Methotrexate1.5%53

Taken alongside

1
Ganciclovir5.4%193
2
Sulfamethoxazole5.3%190
3
Trimethoprim4.9%176
4
Amlodipine4.0%145
5
Furosemide3.6%129
6
Ergocalciferol3.2%116
7
Baclofen3.2%115
8
Pantoprazole-sodium3.1%112
9
Acetaminophen3.1%111
10
Metoprolol3.0%108
11
Omeprazole2.9%103
12
Ciprofloxacin2.7%97
13
Methylprednisolone2.7%96
14
Gabapentin2.6%95
15
Nystatin2.4%88

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports daclizumab side effects

66.0% of daclizumab adverse event reports involve female patients and 26.3% involve male patients. The largest age group is adult at 87%. These figures reflect who reports side effects, not underlying risk.

Sex

Female66.0%
Male26.3%
Unknown7.7%

Age group

< 21.0%
2–113.4%
12–171.9%
18–6487.2%
65+6.4%

What is daclizumab used for

Conditions and purposes for which patients were taking daclizumab when the adverse event was reported.

Acute Graft Versus Host DiseaseAcute Graft Versus Host Disease In IntestineAcute Graft Versus Host Disease In LiverAcute Graft Versus Host Disease In SkinAcute Lymphocytic LeukaemiaAplasia Pure Red CellAplastic AnaemiaAsthmaAutoimmune Haemolytic AnaemiaAplastic AnaemiaBirdshot ChorioretinopathyCentral Nervous System LesionCongenital Nephrotic SyndromeCytopeniaCytopenia

Showing 15 of 76 indications

Daclizumab brand names and reporting trend

Daclizumab is sold under the brand name Zinbryta.

Brand names

Zinbryta2,327

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking daclizumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.