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Crovalimab Side Effects

The most commonly reported side effects of crovalimab include type iii immune complex mediated reaction, anaemia, and pyrexia, based on 73 FDA adverse event reports from 2004 to 2025. 5.5% of reports found the drug to be ineffective.

Crovalimab side effects

Percentages show how often each reaction appears relative to total reports for crovalimab.

1
Type Iii Immune Complex Mediated Reaction24.7%18
2
Anaemia19.2%14
3
Pyrexia16.4%12
4
Off Label Use15.1%11
5
Haemolysis12.3%9
6
Pneumonia8.2%6
7
Infection6.8%5
8
Urinary Tract Infection6.8%5
9
Covid-196.8%5
10
Haemoglobin Decreased5.5%4
11
Hepatic Function Abnormal5.5%4
12
Breakthrough Haemolysis5.5%4
13
Drug Ineffective5.5%4
14
Sepsis4.1%3
15
Cardiac Failure4.1%3

These are voluntary reports and do not establish that crovalimab caused these reactions.

Report severity

97.3%Serious71 reports
54.8%Hospitalizations40 reports
6.8%Fatal5 reports

Seriousness is determined by the reporter, not by OpenClaim.

Crovalimab drug interactions

Other drugs that appear in adverse event reports alongside crovalimab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ravulizumab-cwvz9.6%7
2
Danicopan8.2%6
3
Amphotericin-b1.4%1
4
Dihydrocodeine-bitartrate1.4%1
5
Travoprost1.4%1
6
Allopurinol1.4%1
7
Rabeprazole-sodium1.4%1
8
Lenalidomide1.4%1
9
Adalimumab1.4%1
10
Indapamide1.4%1
11
Valproic-acid1.4%1
12
Estrogens1.4%1
13
Prednisolone1.4%1
14
Glimepiride1.4%1
15
Sitagliptin1.4%1

Taken alongside

1
Acetaminophen6.8%5
2
Prednisone6.8%5
3
Levofloxacin5.5%4
4
Omeprazole4.1%3
5
Ciprofloxacin4.1%3
6
Bisoprolol-fumarate4.1%3
7
Zolpidem-tartrate4.1%3
8
Amlodipine4.1%3
9
Aspirin4.1%3
10
Atorvastatin-calcium4.1%3
11
Prednisolone4.1%3
12
Febuxostat4.1%3
13
Magnesium-oxide4.1%3
14
Carvedilol4.1%3
15
Prochlorperazine2.7%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports crovalimab side effects

43.8% of crovalimab adverse event reports involve female patients and 50.7% involve male patients. The largest age group is elderly at 62%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.8%
Male50.7%
Unknown5.5%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6437.9%
65+62.1%

What is crovalimab used for

Conditions and purposes for which patients were taking crovalimab when the adverse event was reported.

Drug Use For Unknown IndicationNauseaProduct Used For Unknown IndicationParoxysmal Nocturnal HaemoglobinuriaProduct Used For Unknown Indication

Crovalimab brand names and reporting trend

Crovalimab is sold under the brand name Piasky.

Brand names

Piasky18

Quarterly reports (20042025)

20042025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking crovalimab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.