OpenClaim

Crotamiton Side Effects

The most commonly reported side effects of crotamiton include pruritus, nausea, and depression, based on 1,042 FDA adverse event reports from 2004 to 2025.

Crotamiton side effects

Percentages show how often each reaction appears relative to total reports for crotamiton.

1
Pruritus7.3%76
2
Nausea5.2%54
3
Depression4.8%50
4
Rash4.6%48
5
Fatigue4.5%47
6
Diarrhoea4.3%45
7
Dizziness4.2%44
8
Anaemia3.6%38
9
Constipation3.6%37
10
Anxiety3.4%35
11
Malaise3.3%34
12
Pyrexia3.2%33
13
Dyspnoea3.2%33
14
Pain3.0%31
15
Headache3.0%31

These are voluntary reports and do not establish that crotamiton caused these reactions.

Report severity

95.1%Serious991 reports
47.0%Hospitalizations490 reports
11.7%Fatal122 reports

Seriousness is determined by the reporter, not by OpenClaim.

Crotamiton drug interactions

Other drugs that appear in adverse event reports alongside crotamiton. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ivermectin4.8%50
2
Paclitaxel4.7%49
3
Trastuzumab4.0%42
4
Venlafaxine3.6%38
5
Pregabalin3.4%35
6
Ramipril3.2%33
7
Docetaxel3.2%33
8
Atorvastatin-calcium3.1%32
9
Ribavirin2.9%30
10
Letrozole2.8%29
11
Citalopram-hydrobromide2.6%27
12
Capecitabine2.4%25
13
Valsartan2.3%24
14
Mirtazapine2.0%21
15
Risperidone1.9%20

Taken alongside

1
Acetaminophen11.8%123
2
Aspirin11.8%123
3
Hydrocortisone11.6%121
4
Fexofenadine-hydrochloride11.5%120
5
Omeprazole10.7%112
6
Amlodipine9.1%95
7
Prednisolone8.9%93
8
Furosemide8.6%90
9
Cetirizine-hydrochloride8.2%85
10
Albuterol8.1%84
11
Bisoprolol-fumarate7.2%75
12
Insulin6.9%72
13
Magnesium-oxide6.7%70
14
Lansoprazole5.9%61
15
Dexamethasone5.7%59

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports crotamiton side effects

53.5% of crotamiton adverse event reports involve female patients and 39.2% involve male patients. The largest age group is elderly at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female53.5%
Male39.2%
Unknown7.4%

Age group

< 22.1%
2–110.6%
12–170.9%
18–6442.2%
65+54.3%

What is crotamiton used for

Conditions and purposes for which patients were taking crotamiton when the adverse event was reported.

AcarodermatitisAdverse EventAggressionAntidepressant TherapyAntiviral TreatmentAnxiety DisorderArthralgiaArthropod BiteAsteatosisAcarodermatitisAdverse EventAnxiety DisorderBehcet^s SyndromeBorderline Personality DisorderCerebrovascular Accident

Showing 15 of 106 indications

Crotamiton brand names and reporting trend

Crotamiton is sold under the brand name Crotan.

Brand names

Crotan227

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking crotamiton with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.