OpenClaim

Corticorelin Side Effects

The most commonly reported side effects of corticorelin include abdominal pain, vomiting, and drug dose omission, based on 54 FDA adverse event reports from 2004 to 2025. 7.4% of reports found the drug to be ineffective.

Corticorelin side effects

Percentages show how often each reaction appears relative to total reports for corticorelin.

1
Abdominal Pain13.0%7
2
Vomiting9.3%5
3
Drug Dose Omission7.4%4
4
Drug Ineffective7.4%4
5
Infection7.4%4
6
Abdominal Distension7.4%4
7
General Physical Health Deterioration7.4%4
8
Systemic Infection7.4%4
9
Hyponatraemia7.4%4
10
Atrial Fibrillation7.4%4
11
Electrocardiogram Abnormal7.4%4
12
Pancreatitis7.4%4
13
Loss Of Consciousness5.6%3
14
Urinary Retention5.6%3
15
Headache5.6%3

These are voluntary reports and do not establish that corticorelin caused these reactions.

Report severity

90.7%Serious49 reports
51.9%Hospitalizations28 reports
14.8%Fatal8 reports

Seriousness is determined by the reporter, not by OpenClaim.

Corticorelin drug interactions

Other drugs that appear in adverse event reports alongside corticorelin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Esomeprazole7.4%4
2
Tofacitinib7.4%4
3
Lenalidomide7.4%4
4
Vigabatrin5.6%3
5
Lansoprazole5.6%3
6
Fenofibrate5.6%3
7
Adalimumab3.7%2
8
Dexlansoprazole3.7%2
9
Cytarabine3.7%2
10
Doxorubicin-hydrochloride3.7%2
11
Pegaspargase3.7%2
12
Vincristine-sulfate3.7%2
13
Cyclophosphamide3.7%2
14
Methotrexate3.7%2
15
Enzalutamide3.7%2

Taken alongside

1
Aspirin18.5%10
2
Acetaminophen16.7%9
3
Ergocalciferol16.7%9
4
Furosemide14.8%8
5
Simvastatin13.0%7
6
Metformin11.1%6
7
Prednisone11.1%6
8
Formoterol9.3%5
9
Levothyroxine-sodium9.3%5
10
Amlodipine9.3%5
11
Albuterol7.4%4
12
Omeprazole7.4%4
13
Oxycodone7.4%4
14
Calcium7.4%4
15
Ranitidine7.4%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports corticorelin side effects

50.0% of corticorelin adverse event reports involve female patients and 44.4% involve male patients. The largest age group is adult at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.0%
Male44.4%
Unknown5.6%

Age group

< 24.7%
2–117.0%
12–172.3%
18–6455.8%
65+30.2%

What is corticorelin used for

Conditions and purposes for which patients were taking corticorelin when the adverse event was reported.

Acute Lymphocytic LeukaemiaAdrenocorticotropic Hormone DeficiencyAlcoholismBlood Cholesterol AbnormalColitis UlcerativeCoronavirus InfectionCovid-19 PneumoniaCushing's SyndromeDiagnostic ProcedureDrug Use For Unknown IndicationDermatitis AllergicInsomniaLymphodepletionProduct Used For Unknown IndicationPlasma Cell Myeloma Refractory

Showing 15 of 17 indications

Corticorelin brand names and reporting trend

Corticorelin is sold under the brand name Acthrel.

Brand names

Acthrel41

Quarterly reports (20042025)

200520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking corticorelin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.