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Conivaptan Side Effects

The most commonly reported side effects of conivaptan include blood sodium increased, atrial fibrillation, and death, based on 54 FDA adverse event reports from 2006 to 2024. 13.0% of reports found the drug to be ineffective.

Conivaptan side effects

Percentages show how often each reaction appears relative to total reports for conivaptan.

1
Drug Ineffective13.0%7
2
Blood Sodium Increased11.1%6
3
Atrial Fibrillation5.6%3
4
Death5.6%3
5
Extravasation5.6%3
6
Tachycardia3.7%2
7
Hypotension3.7%2
8
Hyponatraemia3.7%2
9
Cardiac Arrest3.7%2
10
Injection Site Extravasation3.7%2
11
Infusion Site Extravasation3.7%2
12
Product Use Issue3.7%2
13
Hypoaesthesia1.9%1
14
Injection Site Phlebitis1.9%1
15
Paraesthesia1.9%1

These are voluntary reports and do not establish that conivaptan caused these reactions.

Report severity

44.4%Serious24 reports
14.8%Hospitalizations8 reports
13.0%Fatal7 reports

Seriousness is determined by the reporter, not by OpenClaim.

Conivaptan drug interactions

Other drugs that appear in adverse event reports alongside conivaptan. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Tolvaptan9.3%5
2
Escitalopram-oxalate1.9%1
3
Verapamil-hydrochloride1.9%1
4
Tacrolimus1.9%1
5
Vasopressin1.9%1
6
Trandolapril1.9%1

Taken alongside

1
Furosemide7.4%4
2
Levofloxacin3.7%2
3
Demeclocycline-hydrochloride3.7%2
4
Labetalol-hydrochloride3.7%2
5
Acetylcysteine3.7%2
6
Pantoprazole-sodium3.7%2
7
Chlorothiazide3.7%2
8
Levothyroxine-sodium3.7%2
9
Warfarin3.7%2
10
Fentanyl1.9%1
11
Niacinamide1.9%1
12
Pyridoxine1.9%1
13
Tyrosine1.9%1
14
Hydromorphone-hydrochloride1.9%1
15
Diazepam1.9%1

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports conivaptan side effects

46.3% of conivaptan adverse event reports involve female patients and 38.9% involve male patients. The largest age group is elderly at 50%. These figures reflect who reports side effects, not underlying risk.

Sex

Female46.3%
Male38.9%
Unknown14.8%

Age group

< 20.0%
2–110.0%
12–1712.5%
18–6437.5%
65+50.0%

What is conivaptan used for

Conditions and purposes for which patients were taking conivaptan when the adverse event was reported.

Blood Sodium DecreasedBrain OedemaCardiac FailureDrug Use For Unknown IndicationHypokalaemiaHyponatraemiaHyponatraemiaInappropriate Antidiuretic Hormone SecretionInappropriate Antidiuretic Hormone SecretionMyocardial IschaemiaOliguriaProduct Used For Unknown Indication

Conivaptan brand names and reporting trend

Conivaptan is sold under the brand name Vaprisol.

Brand names

Vaprisol10

Quarterly reports (20062024)

2006201020152020

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking conivaptan with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.