The most commonly reported side effects of cobimetinib include off label use, diarrhoea, and rash, based on 4,309 FDA adverse event reports from 2013 to 2025.
Percentages show how often each reaction appears relative to total reports for cobimetinib.
These are voluntary reports and do not establish that cobimetinib caused these reactions.
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Other drugs that appear in adverse event reports alongside cobimetinib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
45.0% of cobimetinib adverse event reports involve female patients and 47.0% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking cobimetinib when the adverse event was reported.
Showing 15 of 320 indications
Cobimetinib is sold under the brand name Cotellic.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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