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Clevidipine Side Effects

The most commonly reported side effects of clevidipine include ventilation perfusion mismatch, hypoxia, and hypotension, based on 375 FDA adverse event reports from 2004 to 2025. 6.7% of reports found the drug to be ineffective.

Clevidipine side effects

Percentages show how often each reaction appears relative to total reports for clevidipine.

1
Drug Ineffective6.7%25
2
Ventilation Perfusion Mismatch6.1%23
3
Hypoxia6.1%23
4
Hypotension4.3%16
5
Hypotension4.0%15
6
Atrial Fibrillation3.5%13
7
Extravasation3.5%13
8
Oxygen Saturation Decreased3.2%12
9
Blood Pressure Inadequately Controlled2.9%11
10
Drug Ineffective2.9%11
11
Tachycardia2.9%11
12
Off Label Use2.9%11
13
Bradycardia2.4%9
14
Tachycardia2.1%8
15
Post Procedural Complication2.1%8

These are voluntary reports and do not establish that clevidipine caused these reactions.

Report severity

60.8%Serious228 reports
14.9%Hospitalizations56 reports
6.4%Fatal24 reports

Seriousness is determined by the reporter, not by OpenClaim.

Clevidipine drug interactions

Other drugs that appear in adverse event reports alongside clevidipine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Nicardipine-hydrochloride4.0%15
2
Propofol3.5%13
3
Fentanyl2.4%9
4
Hydralazine-hydrochloride2.1%8
5
Hydromorphone-hydrochloride2.1%8
6
Epinephrine1.9%7
7
Sodium-nitroprusside1.9%7
8
Labetalol-hydrochloride1.9%7
9
Metoprolol1.3%5
10
Phenylephrine1.3%5
11
Ketamine-hydrochloride1.3%5
12
Adalimumab1.1%4
13
Midazolam1.1%4
14
Furosemide1.1%4
15
Amlodipine1.1%4

Taken alongside

1
Propofol6.1%23
2
Acetaminophen5.9%22
3
Metoprolol5.6%21
4
Amlodipine5.3%20
5
Labetalol-hydrochloride4.8%18
6
Aspirin4.3%16
7
Fentanyl4.0%15
8
Hydralazine-hydrochloride4.0%15
9
Nitroglycerin4.0%15
10
Insulin3.7%14
11
Furosemide3.7%14
12
Atorvastatin-calcium3.2%12
13
Nicardipine-hydrochloride2.9%11
14
Lisinopril2.7%10
15
Pantoprazole-sodium2.4%9

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports clevidipine side effects

19.5% of clevidipine adverse event reports involve female patients and 32.5% involve male patients. The largest age group is adult at 59%. These figures reflect who reports side effects, not underlying risk.

Sex

Female19.5%
Male32.5%
Unknown48.0%

Age group

< 20.0%
2–112.2%
12–171.1%
18–6458.9%
65+37.8%

What is clevidipine used for

Conditions and purposes for which patients were taking clevidipine when the adverse event was reported.

Aortic DissectionBlood PressureBlood Pressure AbnormalBlood Pressure DecreasedBlood Pressure Inadequately ControlledBlood Pressure IncreasedBlood Pressure ManagementBlood Pressure MeasurementBlood Pressure Systolic IncreasedBlood Pressure IncreasedBlood Pressure ManagementBlood Pressure MeasurementBlood Pressure SystolicCardiac OperationCarotid Endarterectomy

Showing 15 of 45 indications

Clevidipine brand names and reporting trend

Clevidipine is sold under the brand name Cleviprex.

Brand names

Cleviprex89

Quarterly reports (20042025)

2005201020202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking clevidipine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.