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Citric Side Effects

The most commonly reported side effects of citric include nausea, vomiting, and off label use, based on 1,981 FDA adverse event reports from 2004 to 2025. 27.1% of reports found the drug to be ineffective.

Citric side effects

Percentages show how often each reaction appears relative to total reports for citric.

1
Drug Ineffective27.1%537
2
Nausea13.3%263
3
Vomiting11.3%224
4
Off Label Use8.8%174
5
Headache8.2%162
6
Diarrhoea7.1%141
7
Abdominal Pain6.8%135
8
Pain5.4%107
9
Abdominal Distension5.2%104
10
Malaise5.1%101
11
Drug Hypersensitivity5.1%101
12
Constipation5.0%100
13
Anaemia4.6%91
14
Hyponatraemia4.1%82
15
Dizziness4.0%80

These are voluntary reports and do not establish that citric caused these reactions.

Report severity

41.5%Serious822 reports
18.6%Hospitalizations368 reports
6.8%Fatal135 reports

Seriousness is determined by the reporter, not by OpenClaim.

Citric drug interactions

Other drugs that appear in adverse event reports alongside citric. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Magnesium-oxide59.5%1,179
2
Sodium-picosulfate59.1%1,171
3
Acetaminophen8.2%163
4
Lactic-acid7.8%155
5
Potassium-bitartrate7.8%155
6
Simvastatin7.6%151
7
Potassium-chloride7.3%144
8
Hydrocortisone7.0%139
9
Sodium-chloride6.6%130
10
Heparin6.3%125
11
Metronidazole6.3%124
12
Lansoprazole6.3%124
13
Dobutamine-hydrochloride6.3%124
14
Albuterol6.2%123
15
Dalteparin-sodium6.2%122

Taken alongside

1
Ergocalciferol9.8%194
2
Magnesium-oxide9.0%178
3
Acetaminophen8.6%171
4
Sodium-picosulfate8.2%162
5
Aspirin7.9%156
6
Levothyroxine-sodium6.1%120
7
Pantoprazole-sodium6.0%118
8
Omeprazole6.0%118
9
Albuterol5.7%112
10
Amlodipine5.2%103
11
Ascorbic-acid4.8%95
12
Atorvastatin-calcium4.7%93
13
Fluticasone4.7%93
14
Ondansetron4.2%84
15
Furosemide4.0%80

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports citric side effects

53.8% of citric adverse event reports involve female patients and 30.7% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female53.8%
Male30.7%
Unknown15.5%

Age group

< 21.0%
2–110.9%
12–170.3%
18–6454.2%
65+43.5%

What is citric used for

Conditions and purposes for which patients were taking citric when the adverse event was reported.

Adrenal InsufficiencyAnaemiaAntiallergic TherapyAbdominal DiscomfortAntacid TherapyAnticoagulant TherapyBlood PotassiumBlood Potassium DecreasedBowel PreparationBladder IrrigationBlood Pressure IncreasedBowel PreparationColonoscopyConstipationContraception

Showing 15 of 76 indications

Citric brand names and reporting trend

Citric is sold under the brand name Clenpiq.

Brand names

Clenpiq684

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking citric with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.