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Citalopram Side Effects

The most commonly reported side effects of citalopram include fatigue, nausea, and headache, based on 139,243 FDA adverse event reports from 2004 to 2025. 4.7% of reports found the drug to be ineffective.

Citalopram side effects

Percentages show how often each reaction appears relative to total reports for citalopram.

1
Fatigue5.7%7,935
2
Nausea4.9%6,784
3
Drug Ineffective4.7%6,502
4
Headache4.1%5,683
5
Diarrhoea3.9%5,394
6
Off Label Use3.7%5,132
7
Toxicity To Various Agents3.7%5,101
8
Pain3.6%4,973
9
Fall3.3%4,641
10
Dizziness3.3%4,599
11
Dyspnoea3.1%4,379
12
Anxiety3.1%4,277
13
Depression2.8%3,892
14
Vomiting2.8%3,892
15
Malaise2.6%3,686

These are voluntary reports and do not establish that citalopram caused these reactions.

Report severity

77.4%Serious107,826 reports
33.8%Hospitalizations47,028 reports
14.1%Fatal19,669 reports

Seriousness is determined by the reporter, not by OpenClaim.

Citalopram drug interactions

Other drugs that appear in adverse event reports alongside citalopram. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Quetiapine-fumarate4.2%5,796
2
Adalimumab3.9%5,461
3
Acetaminophen2.8%3,941
4
Bupropion2.4%3,408
5
Omeprazole2.2%3,029
6
Lenalidomide2.2%3,019
7
Gabapentin2.1%2,959
8
Olanzapine1.8%2,559
9
Oxycodone1.8%2,553
10
Alprazolam1.8%2,550
11
Pantoprazole-sodium1.7%2,366
12
Sodium-oxybate1.7%2,306
13
Risperidone1.6%2,247
14
Mirtazapine1.6%2,236
15
Infliximab1.6%2,177

Taken alongside

1
Acetaminophen13.4%18,659
2
Aspirin11.3%15,752
3
Omeprazole10.8%15,041
4
Levothyroxine-sodium10.8%15,028
5
Ergocalciferol9.6%13,337
6
Gabapentin8.6%11,998
7
Atorvastatin-calcium8.3%11,552
8
Albuterol8.3%11,520
9
Furosemide7.5%10,505
10
Amlodipine6.9%9,624
11
Pantoprazole-sodium6.7%9,339
12
Metformin6.6%9,151
13
Lisinopril6.4%8,906
14
Simvastatin6.3%8,757
15
Metoprolol6.3%8,751

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports citalopram side effects

62.3% of citalopram adverse event reports involve female patients and 30.5% involve male patients. The largest age group is adult at 65%. These figures reflect who reports side effects, not underlying risk.

Sex

Female62.3%
Male30.5%
Unknown7.2%

Age group

< 21.4%
2–110.3%
12–171.5%
18–6465.2%
65+31.6%

What is citalopram used for

Conditions and purposes for which patients were taking citalopram when the adverse event was reported.

Abdominal DiscomfortAbdominal PainAbdominal Pain UpperAbnormal BehaviourAbnormal DreamsAccidentAccidental ExposureAccidental Exposure To Product By ChildAcneAcromegalyAcute PsychosisAcute Stress DisorderAdjustment DisorderAdjustment Disorder With Depressed MoodAdjustment Disorder With Mixed Anxiety And Depressed Mood

Showing 15 of 910 indications

Citalopram brand names and reporting trend

Citalopram is sold under the brand name Celexa.

Brand names

Celexa119,388

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking citalopram with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.