OpenClaim

Cisapride Side Effects

The most commonly reported side effects of cisapride include electrocardiogram qt prolonged, electrocardiogram qt prolonged, and anxiety, based on 1,161 FDA adverse event reports from 2004 to 2025. 2.2% of reports found the drug to be ineffective.

Cisapride side effects

Percentages show how often each reaction appears relative to total reports for cisapride.

1
Electrocardiogram Qt Prolonged19.8%230
2
Electrocardiogram Qt Prolonged4.7%54
3
Anxiety3.0%35
4
Chest Pain2.8%33
5
Dyspnoea2.8%32
6
Pain2.7%31
7
Chronic Kidney Disease2.6%30
8
Hypertension2.5%29
9
Myocardial Infarction2.5%29
10
Vomiting2.5%29
11
Renal Failure2.5%29
12
Vomiting2.5%29
13
Nausea2.4%28
14
Depression2.2%26
15
Drug Interaction2.2%26

These are voluntary reports and do not establish that cisapride caused these reactions.

Report severity

92.7%Serious1,076 reports
38.3%Hospitalizations445 reports
19.4%Fatal225 reports

Seriousness is determined by the reporter, not by OpenClaim.

Cisapride drug interactions

Other drugs that appear in adverse event reports alongside cisapride. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Omeprazole5.9%68
2
Lansoprazole3.9%45
3
Metoclopramide-hydrochloride3.4%39
4
Esomeprazole3.4%39
5
Pantoprazole-sodium2.0%23
6
Rofecoxib1.9%22
7
Gabapentin1.9%22
8
Levetiracetam1.9%22
9
Ranitidine1.7%20
10
Clonidine1.6%18
11
Clonazepam1.6%18
12
Lacosamide1.6%18
13
Vigabatrin1.5%17
14
Valproic-acid1.3%15
15
Digoxin1.2%14

Taken alongside

1
Omeprazole18.6%216
2
Acetaminophen17.7%205
3
Lansoprazole13.6%158
4
Ranitidine11.0%128
5
Albuterol10.9%126
6
Aspirin8.9%103
7
Furosemide8.4%98
8
Levothyroxine-sodium7.8%91
9
Gabapentin6.8%79
10
Insulin6.8%79
11
Fluticasone6.7%78
12
Ibuprofen6.6%77
13
Esomeprazole6.5%76
14
Lorazepam6.3%73
15
Polyethylene-glycol-33506.2%72

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports cisapride side effects

61.9% of cisapride adverse event reports involve female patients and 32.6% involve male patients. The largest age group is adult at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female61.9%
Male32.6%
Unknown5.4%

Age group

< 27.4%
2–1111.5%
12–174.3%
18–6452.1%
65+24.7%

What is cisapride used for

Conditions and purposes for which patients were taking cisapride when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal Pain UpperAbdominal Wall HaematomaAnaemiaAnxietyAppetite DisorderArthritisAspirationAdverse EventBarrett's OesophagusBlood Pressure AbnormalBronchial HyperactivityConstipationConvulsion

Showing 15 of 82 indications

Cisapride brand names and reporting trend

Cisapride is sold under the brand name Propulsid Quicksolv.

Brand names

Propulsid Quicksolv1,367

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking cisapride with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.