OpenClaim

Ciclopirox Side Effects

The most commonly reported side effects of ciclopirox include fatigue, pain, and diarrhoea, based on 3,705 FDA adverse event reports from 2004 to 2025. 13.6% of reports found the drug to be ineffective.

Ciclopirox side effects

Percentages show how often each reaction appears relative to total reports for ciclopirox.

1
Drug Ineffective13.6%503
2
Fatigue6.4%237
3
Pain5.4%199
4
Diarrhoea5.3%196
5
Pruritus4.7%174
6
Rash4.5%168
7
Headache4.5%165
8
Off Label Use4.3%161
9
Dyspnoea4.3%158
10
Nausea4.2%156
11
Arthralgia3.8%140
12
Dizziness3.5%130
13
Fall3.5%130
14
Pain In Extremity3.0%112
15
Product Use In Unapproved Indication3.0%112

These are voluntary reports and do not establish that ciclopirox caused these reactions.

Report severity

56.3%Serious2,085 reports
27.3%Hospitalizations1,011 reports
4.3%Fatal160 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ciclopirox drug interactions

Other drugs that appear in adverse event reports alongside ciclopirox. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Dupilumab5.5%204
2
Lenalidomide4.3%160
3
Sodium-oxybate3.6%134
4
Hydrocortisone2.9%107
5
Aspirin2.9%106
6
Amlodipine2.7%100
7
Dexlansoprazole2.7%99
8
Levothyroxine-sodium2.6%95
9
Omeprazole2.5%94
10
Mometasone-furoate2.5%94
11
Adalimumab2.5%92
12
Escitalopram-oxalate2.5%92
13
Testosterone2.5%91
14
Terbinafine2.4%90
15
Rosuvastatin2.4%90

Taken alongside

1
Acetaminophen22.1%817
2
Ergocalciferol20.8%769
3
Aspirin18.0%666
4
Albuterol15.3%568
5
Atorvastatin-calcium15.0%556
6
Levothyroxine-sodium14.8%549
7
Fluticasone13.8%513
8
Gabapentin12.8%475
9
Prednisone12.4%461
10
Amlodipine12.4%459
11
Omeprazole12.4%458
12
Metformin11.4%422
13
Furosemide11.3%417
14
Triamcinolone10.9%404
15
Ondansetron9.9%365

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ciclopirox side effects

49.1% of ciclopirox adverse event reports involve female patients and 37.1% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female49.1%
Male37.1%
Unknown13.7%

Age group

< 20.2%
2–110.7%
12–170.8%
18–6453.3%
65+45.0%

What is ciclopirox used for

Conditions and purposes for which patients were taking ciclopirox when the adverse event was reported.

Accidental Exposure To ProductAcneAlopeciaAlopecia ScarringAlternaria InfectionAnal PruritusAntifungal ProphylaxisAntifungal TreatmentApplication Site DermatitisAtopyAlopeciaAlopecia AreataAntifungal ProphylaxisAntifungal TreatmentAtopy

Showing 15 of 174 indications

Ciclopirox brand names and reporting trend

Ciclopirox is sold under the brand name Penlac.

Brand names

Penlac3,461

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ciclopirox with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.