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Ciclesonide Side Effects

The most commonly reported side effects of ciclesonide include asthma, dyspnoea, and wheezing, based on 13,571 FDA adverse event reports from 2006 to 2025. 11.1% of reports found the drug to be ineffective.

Ciclesonide side effects

Percentages show how often each reaction appears relative to total reports for ciclesonide.

1
Asthma41.7%5,658
2
Dyspnoea32.8%4,456
3
Wheezing26.4%3,579
4
Therapeutic Product Effect Incomplete18.8%2,550
5
Cough18.1%2,460
6
Obstructive Airways Disorder12.9%1,750
7
Loss Of Personal Independence In Daily Activities12.8%1,735
8
Pneumonia12.4%1,678
9
Drug Ineffective11.1%1,508
10
Productive Cough10.7%1,457
11
Sleep Disorder Due To A General Medical Condition10.6%1,439
12
Fatigue9.0%1,228
13
Chest Discomfort8.6%1,161
14
Malaise8.2%1,110
15
Condition Aggravated7.7%1,046

These are voluntary reports and do not establish that ciclesonide caused these reactions.

Report severity

89.7%Serious12,179 reports
44.3%Hospitalizations6,013 reports
4.5%Fatal604 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ciclesonide drug interactions

Other drugs that appear in adverse event reports alongside ciclesonide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Albuterol28.5%3,869
2
Tiotropium-bromide20.8%2,828
3
Mepolizumab20.8%2,824
4
Prednisone19.7%2,672
5
Fluticasone16.9%2,300
6
Omalizumab16.6%2,259
7
Montelukast-sodium16.5%2,240
8
Budesonide16.4%2,224
9
Formoterol13.5%1,830
10
Ipratropium-bromide9.3%1,265
11
Salmeterol-xinafoate8.9%1,206
12
Vilanterol-trifenatate7.1%968
13
Azithromycin5.9%799
14
Pantoprazole-sodium5.1%697
15
Umeclidinium-bromide5.1%686

Taken alongside

1
Albuterol28.7%3,893
2
Montelukast-sodium17.1%2,316
3
Prednisone14.6%1,987
4
Fluticasone13.2%1,790
5
Tiotropium-bromide12.2%1,654
6
Budesonide11.6%1,568
7
Formoterol10.3%1,397
8
Acetaminophen10.2%1,379
9
Pantoprazole-sodium9.0%1,219
10
Ergocalciferol8.8%1,198
11
Levothyroxine-sodium8.6%1,167
12
Salmeterol-xinafoate8.3%1,129
13
Furosemide6.6%896
14
Diphenhydramine6.1%831
15
Cetirizine-hydrochloride6.1%830

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ciclesonide side effects

59.6% of ciclesonide adverse event reports involve female patients and 31.4% involve male patients. The largest age group is adult at 54%. These figures reflect who reports side effects, not underlying risk.

Sex

Female59.6%
Male31.4%
Unknown9.0%

Age group

< 20.3%
2–112.8%
12–171.5%
18–6454.2%
65+41.2%

What is ciclesonide used for

Conditions and purposes for which patients were taking ciclesonide when the adverse event was reported.

Acute Respiratory Distress SyndromeAcute SinusitisAdenoiditisAdjuvant TherapyAdrenocortical Steroid TherapyAdverse EventAllergy ProphylaxisAllergy To PlantsAortic StenosisAphoniaAspirin-exacerbated Respiratory DiseaseAsthmaAsthma BronchialAsthma Exercise InducedAsthma Prophylaxis

Showing 15 of 191 indications

Ciclesonide brand names and reporting trend

Ciclesonide is sold under the brand name Zetonna.

Brand names

Zetonna2,814

Quarterly reports (20062025)

20062010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ciclesonide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.