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Chlortetracycline Side Effects

The most commonly reported side effects of chlortetracycline include inflammatory bowel disease, arthralgia, and diarrhoea, based on 79 FDA adverse event reports from 2004 to 2025.

Chlortetracycline side effects

Percentages show how often each reaction appears relative to total reports for chlortetracycline.

1
Inflammatory Bowel Disease6.3%5
2
Arthralgia6.3%5
3
Diarrhoea6.3%5
4
Nausea6.3%5
5
Pyrexia6.3%5
6
Hypokalaemia6.3%5
7
Diarrhoea5.1%4
8
Anaemia5.1%4
9
Erythema5.1%4
10
Acute Kidney Injury5.1%4
11
Proteinuria5.1%4
12
Urinary Tract Infection5.1%4
13
Pneumonia5.1%4
14
Hypocalcaemia5.1%4
15
Alanine Aminotransferase Increased5.1%4

These are voluntary reports and do not establish that chlortetracycline caused these reactions.

Report severity

89.9%Serious71 reports
39.2%Hospitalizations31 reports
13.9%Fatal11 reports

Seriousness is determined by the reporter, not by OpenClaim.

Chlortetracycline drug interactions

Other drugs that appear in adverse event reports alongside chlortetracycline. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Isotretinoin10.1%8
2
Rituximab10.1%8
3
Methotrexate8.9%7
4
Polatuzumab-vedotin-piiq8.9%7
5
Cyclophosphamide8.9%7
6
Doxorubicin-hydrochloride8.9%7
7
Methylprednisolone6.3%5
8
Ceftriaxone-sodium5.1%4
9
Drospirenone5.1%4
10
Ethinyl-estradiol5.1%4
11
Docetaxel5.1%4
12
Infliximab5.1%4
13
Adalimumab5.1%4
14
Zanubrutinib5.1%4
15
Bevacizumab3.8%3

Taken alongside

1
Acetaminophen21.5%17
2
Furosemide17.7%14
3
Omeprazole15.2%12
4
Dexamethasone15.2%12
5
Potassium-chloride13.9%11
6
Sulfamethoxazole13.9%11
7
Promethazine-hydrochloride12.7%10
8
Trimethoprim11.4%9
9
Sodium-bicarbonate11.4%9
10
Methylprednisolone11.4%9
11
Vancomycin10.1%8
12
Sodium-chloride10.1%8
13
Meropenem10.1%8
14
Doxycycline8.9%7
15
Estropipate8.9%7

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports chlortetracycline side effects

53.2% of chlortetracycline adverse event reports involve female patients and 40.5% involve male patients. The largest age group is adult at 55%. These figures reflect who reports side effects, not underlying risk.

Sex

Female53.2%
Male40.5%
Unknown6.3%

Age group

< 21.6%
2–114.8%
12–174.8%
18–6454.8%
65+33.9%

What is chlortetracycline used for

Conditions and purposes for which patients were taking chlortetracycline when the adverse event was reported.

Achromobacter InfectionAcneAntifungal ProphylaxisBiopsy BoneBorrelia InfectionCentral Venous Catheter RemovalDermatitis ContactEyelid InfectionGingivitis UlcerativeGlomerulonephritisHelicobacter GastritisHordeolumInfection ProphylaxisLacrimation IncreasedNail Bed Infection

Showing 15 of 24 indications

Chlortetracycline brand names and reporting trend

Chlortetracycline is sold under the brand name Aureomycin.

Brand names

Aureomycin51

Quarterly reports (20042025)

2004201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking chlortetracycline with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.