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Chlorprothixene Side Effects

The most commonly reported side effects of chlorprothixene include toxicity to various agents, drug interaction, and suicidal ideation, based on 924 FDA adverse event reports from 2004 to 2025. 11.9% of reports found the drug to be ineffective.

Chlorprothixene side effects

Percentages show how often each reaction appears relative to total reports for chlorprothixene.

1
Toxicity To Various Agents15.6%144
2
Drug Interaction12.3%114
3
Drug Ineffective11.9%110
4
Suicidal Ideation7.5%69
5
Suicide Attempt7.0%65
6
Anxiety6.4%59
7
Somnolence6.4%59
8
Weight Increased6.1%56
9
Off Label Use6.0%55
10
Tremor5.5%51
11
Restlessness5.1%47
12
Intentional Overdose5.0%46
13
Dizziness5.0%46
14
Neuroleptic Malignant Syndrome4.8%44
15
Fatigue4.7%43

These are voluntary reports and do not establish that chlorprothixene caused these reactions.

Report severity

98.6%Serious911 reports
56.6%Hospitalizations523 reports
17.0%Fatal157 reports

Seriousness is determined by the reporter, not by OpenClaim.

Chlorprothixene drug interactions

Other drugs that appear in adverse event reports alongside chlorprothixene. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Quetiapine-fumarate26.8%248
2
Olanzapine16.6%153
3
Risperidone14.7%136
4
Aripiprazole12.6%116
5
Venlafaxine10.2%94
6
Haloperidol9.4%87
7
Clozapine8.0%74
8
Lamotrigine7.8%72
9
Lithium7.6%70
10
Sertraline-hydrochloride7.5%69
11
Valproate-sodium7.4%68
12
Mirtazapine7.3%67
13
Levomepromazine6.8%63
14
Lorazepam6.4%59
15
Diazepam6.2%57

Taken alongside

1
Olanzapine5.1%47
2
Sertraline-hydrochloride5.0%46
3
Diazepam4.7%43
4
Lorazepam3.9%36
5
Quetiapine-fumarate3.9%36
6
Oxazepam3.6%33
7
Pantoprazole-sodium3.6%33
8
Lamotrigine3.6%33
9
Levothyroxine-sodium3.6%33
10
Mirtazapine3.2%30
11
Budesonide2.9%27
12
Ivabradine2.8%26
13
Midazolam2.7%25
14
Citalopram-hydrobromide2.6%24
15
Aripiprazole2.6%24

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports chlorprothixene side effects

50.9% of chlorprothixene adverse event reports involve female patients and 39.8% involve male patients. The largest age group is adult at 82%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.9%
Male39.8%
Unknown9.3%

Age group

< 22.2%
2–110.9%
12–174.0%
18–6481.7%
65+11.1%

What is chlorprothixene used for

Conditions and purposes for which patients were taking chlorprothixene when the adverse event was reported.

Abnormal BehaviourAcute PsychosisAgitationAlcohol AbuseAnxietyAnxiety DisorderAttention Deficit/hyperactivity DisorderAutism Spectrum DisorderAgitationAlcohol AbuseAnorexia NervosaAntidepressant TherapyAnxietyAnxiety DisorderAutism Spectrum Disorder

Showing 15 of 88 indications

Chlorprothixene brand names and reporting trend

Chlorprothixene is sold under the brand name Taractan.

Brand names

Taractan1,102

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking chlorprothixene with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.