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Chlorphentermine Side Effects

The most commonly reported side effects of chlorphentermine include nausea, rash, and oedema peripheral, based on 19 FDA adverse event reports from 2007 to 2025.

Chlorphentermine side effects

Percentages show how often each reaction appears relative to total reports for chlorphentermine.

1
Nausea15.8%3
2
Rash15.8%3
3
Oedema Peripheral10.5%2
4
Vomiting10.5%2
5
Joint Swelling5.3%1
6
Ligament Rupture5.3%1
7
Myoclonus5.3%1
8
Ecchymosis5.3%1
9
Haemorrhage5.3%1
10
Myocardial Infarction5.3%1
11
Platelet Count Decreased5.3%1
12
Diabetes Mellitus5.3%1
13
Fatigue5.3%1
14
Intestinal Obstruction5.3%1
15
Sepsis5.3%1

These are voluntary reports and do not establish that chlorphentermine caused these reactions.

Report severity

63.2%Serious12 reports
26.3%Hospitalizations5 reports
15.8%Fatal3 reports

Seriousness is determined by the reporter, not by OpenClaim.

Chlorphentermine drug interactions

Other drugs that appear in adverse event reports alongside chlorphentermine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Dimethyl10.5%2
2
Fentanyl5.3%1
3
Risperidone5.3%1
4
Sevelamer5.3%1
5
Amlodipine5.3%1
6
Valsartan5.3%1
7
Hydrochlorothiazide5.3%1
8
Fingolimod5.3%1
9
Metformin5.3%1
10
Sitagliptin5.3%1
11
Methotrexate5.3%1
12
Adalimumab5.3%1
13
Sodium-oxybate5.3%1
14
Sunitinib-malate5.3%1
15
Ixekizumab5.3%1

Taken alongside

1
Oxycodone26.3%5
2
Acetaminophen21.1%4
3
Hydrocodone21.1%4
4
Alprazolam21.1%4
5
Ibuprofen21.1%4
6
Gabapentin15.8%3
7
Carisoprodol15.8%3
8
Levothyroxine-sodium15.8%3
9
Mometasone-furoate15.8%3
10
Ergocalciferol15.8%3
11
Trazodone-hydrochloride15.8%3
12
Montelukast-sodium15.8%3
13
Diazepam10.5%2
14
Ranitidine10.5%2
15
Metoprolol10.5%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports chlorphentermine side effects

63.2% of chlorphentermine adverse event reports involve female patients and 31.6% involve male patients. The largest age group is adult at 67%. These figures reflect who reports side effects, not underlying risk.

Sex

Female63.2%
Male31.6%
Unknown5.3%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6466.7%
65+33.3%

What is chlorphentermine used for

Conditions and purposes for which patients were taking chlorphentermine when the adverse event was reported.

CoughDrug Use For Unknown IndicationHypertensionNasal Decongestion TherapyProduct Use In Unapproved IndicationProduct Used For Unknown Indication

Chlorphentermine brand names and reporting trend

Chlorphentermine is sold under the brand name Pre-sate.

Brand names

Pre-sate16

Quarterly reports (20072025)

20072025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking chlorphentermine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.