The most commonly reported side effects of chlorhexidine include rash, fatigue, and pain, based on 22,125 FDA adverse event reports from 2004 to 2025.
Percentages show how often each reaction appears relative to total reports for chlorhexidine.
These are voluntary reports and do not establish that chlorhexidine caused these reactions.
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Other drugs that appear in adverse event reports alongside chlorhexidine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.
Also suspected
Taken alongside
Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.
57.8% of chlorhexidine adverse event reports involve female patients and 23.9% involve male patients. The largest age group is adult at 69%. These figures reflect who reports side effects, not underlying risk.
Sex
Age group
Conditions and purposes for which patients were taking chlorhexidine when the adverse event was reported.
Showing 15 of 566 indications
Chlorhexidine is sold under the brand name Hibistat.
An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.
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