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Chlordiazepoxide Side Effects

The most commonly reported side effects of chlordiazepoxide include toxicity to various agents, drug abuse, and fatigue, based on 6,412 FDA adverse event reports from 2004 to 2025. 4.4% of reports found the drug to be ineffective.

Chlordiazepoxide side effects

Percentages show how often each reaction appears relative to total reports for chlordiazepoxide.

1
Toxicity To Various Agents4.9%314
2
Drug Ineffective4.4%279
3
Drug Abuse4.3%274
4
Fatigue3.9%253
5
Diarrhoea3.7%237
6
Off Label Use3.6%234
7
Nausea3.4%221
8
Headache3.3%212
9
Dizziness3.0%190
10
Nausea2.9%187
11
Pain2.9%186
12
Drug Interaction2.8%179
13
Fall2.6%166
14
Malaise2.6%164
15
Anxiety2.4%152

These are voluntary reports and do not establish that chlordiazepoxide caused these reactions.

Report severity

71.5%Serious4,584 reports
33.0%Hospitalizations2,115 reports
17.7%Fatal1,135 reports

Seriousness is determined by the reporter, not by OpenClaim.

Chlordiazepoxide drug interactions

Other drugs that appear in adverse event reports alongside chlordiazepoxide. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Diazepam5.9%380
2
Adalimumab5.1%328
3
Acetaminophen4.4%281
4
Quetiapine-fumarate3.6%233
5
Oxycodone3.6%228
6
Clidinium-bromide3.4%220
7
Omeprazole3.0%193
8
Lorazepam2.8%178
9
Alprazolam2.7%174
10
Amitriptyline-hydrochloride2.7%173
11
Alcohol2.7%173
12
Gabapentin2.5%163
13
Pregabalin2.4%157
14
Esomeprazole2.4%152
15
Sodium-oxybate2.3%150

Taken alongside

1
Clidinium-bromide28.8%1,849
2
Acetaminophen17.7%1,138
3
Omeprazole12.9%828
4
Aspirin11.4%731
5
Levothyroxine-sodium11.1%710
6
Albuterol9.3%595
7
Ergocalciferol9.3%595
8
Gabapentin8.8%565
9
Furosemide8.2%524
10
Atorvastatin-calcium7.8%503
11
Metoprolol7.8%497
12
Hydrocodone7.4%476
13
Pantoprazole-sodium7.2%464
14
Alprazolam7.1%456
15
Amitriptyline-hydrochloride6.8%438

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports chlordiazepoxide side effects

60.5% of chlordiazepoxide adverse event reports involve female patients and 34.2% involve male patients. The largest age group is adult at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female60.5%
Male34.2%
Unknown5.3%

Age group

< 20.2%
2–110.3%
12–170.5%
18–6465.7%
65+33.3%

What is chlordiazepoxide used for

Conditions and purposes for which patients were taking chlordiazepoxide when the adverse event was reported.

Abdominal AdhesionsAbdominal DiscomfortAbdominal DistensionAbdominal PainAbdominal Pain UpperAbdominal RigidityAbdominal SymptomAbstains From AlcoholAccidental ExposureAccidental OverdoseAdverse EventAgitationAkathisiaAlcohol AbuseAlcohol Detoxification

Showing 15 of 280 indications

Chlordiazepoxide brand names and reporting trend

Chlordiazepoxide is sold under brand names including Chlordiazepoxide And Amitriptyline Hydrochloride, Chlordiazepoxide Hydrochloride And Clidinium Bromide.

Brand names

Chlordiazepoxide And Amitriptyline Hydrochloride3,052
Chlordiazepoxide Hydrochloride And Clidinium Bromide101

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking chlordiazepoxide with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.