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Cenegermin Side Effects

The most commonly reported side effects of cenegermin include eye pain, eye irritation, and product dose omission issue, based on 11,968 FDA adverse event reports from 2019 to 2025. 4.2% of reports found the drug to be ineffective.

#1 Reported: Eye PainAll side effects ↓Top Co-Medication: CorticotropinDrug interactions ↓66% of Reports Are ElderlyDemographics ↓

Cenegermin side effects

Percentages show how often each reaction appears relative to total reports for cenegermin.

1
Eye Pain48.9%5,851
2
Eye Irritation15.7%1,873
3
Product Dose Omission Issue11.2%1,339
4
Ocular Hyperaemia10.3%1,227
5
Photophobia8.9%1,065
6
Vision Blurred7.9%945
7
Wrong Technique In Product Usage Process7.5%902
8
Eye Swelling7.1%847
9
Ocular Discomfort6.7%798
10
Lacrimation Increased6.2%737
11
Eyelid Pain5.9%707
12
Headache5.6%673
13
Product Administration Error5.1%614
14
Dry Eye4.5%540
15
Off Label Use4.4%524

These are voluntary reports and do not establish that cenegermin caused these reactions.

Report severity

11.7%Serious1,401 reports
6.3%Hospitalizations751 reports
1.7%Fatal201 reports

Seriousness is determined by the reporter, not by OpenClaim.

Cenegermin drug interactions

Other drugs that appear in adverse event reports alongside cenegermin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Corticotropin<0.1%10
2
Moxifloxacin-hydrochloride<0.1%8
3
Prednisone<0.1%6
4
Lifitegrast<0.1%5
5
Timolol<0.1%4
6
Brimonidine-tartrate<0.1%4
7
Latanoprost<0.1%3
8
Fluorometholone<0.1%3
9
Ganciclovir<0.1%3
10
Ciprofloxacin<0.1%3
11
Natamycin<0.1%3
12
Dupilumab<0.1%3
13
Polymyxin-b-sulfate<0.1%2
14
Trimethoprim<0.1%2
15
Loteprednol-etabonate<0.1%2

Taken alongside

1
Ergocalciferol19.0%2,273
2
Levothyroxine-sodium15.5%1,860
3
Aspirin14.8%1,773
4
Atorvastatin-calcium13.9%1,663
5
Cyclosporine13.7%1,637
6
Prednisolone11.6%1,394
7
Gabapentin11.5%1,373
8
Metoprolol10.9%1,310
9
Acyclovir10.1%1,213
10
Acetaminophen9.5%1,140
11
Omeprazole9.1%1,090
12
Moxifloxacin-hydrochloride8.8%1,057
13
Amlodipine8.7%1,038
14
Timolol8.6%1,028
15
Lisinopril7.8%933

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports cenegermin side effects

67.5% of cenegermin adverse event reports involve female patients and 28.9% involve male patients. The largest age group is elderly at 66%. These figures reflect who reports side effects, not underlying risk.

Sex

Female67.5%
Male28.9%
Unknown3.6%

Age group

< 2<0.1%
2–110.4%
12–170.2%
18–6432.8%
65+66.5%

What is cenegermin used for

Conditions and purposes for which patients were taking cenegermin when the adverse event was reported.

Acanthamoeba KeratitisAnophthalmosAstigmatismAbdominal Pain LowerAge-related Macular DegenerationAnaesthesia EyeBlindnessBlepharitisBlindness UnilateralBullous KeratopathyCataract NuclearCellulitis OrbitalCongenital Herpes Simplex InfectionConjunctival DisorderCorneal Abrasion

Showing 15 of 148 indications

Cenegermin brand names and reporting trend

Cenegermin is sold under the brand name Oxervate.

Brand names

Oxervate15

Quarterly reports (2019–2025)

20192020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking cenegermin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

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