OpenClaim

Ceftobiprole Side Effects

The most commonly reported side effects of ceftobiprole include epilepsy, torsade de pointes, and off label use, based on 41 FDA adverse event reports from 2017 to 2025.

Ceftobiprole side effects

Percentages show how often each reaction appears relative to total reports for ceftobiprole.

1
Epilepsy17.1%7
2
Torsade De Pointes14.6%6
3
Off Label Use14.6%6
4
Gangrene12.2%5
5
Pneumonia Necrotising12.2%5
6
Alveolar Lung Disease12.2%5
7
Pancytopenia7.3%3
8
Chest Pain4.9%2
9
Dyspnoea Exertional4.9%2
10
Headache4.9%2
11
Vomiting4.9%2
12
Thrombocytopenia4.9%2
13
Stevens-johnson Syndrome4.9%2
14
Drug Reaction With Eosinophilia And Systemic Symptoms4.9%2
15
Myelosuppression4.9%2

These are voluntary reports and do not establish that ceftobiprole caused these reactions.

Report severity

100.0%Serious41 reports
61.0%Hospitalizations25 reports
2.4%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ceftobiprole drug interactions

Other drugs that appear in adverse event reports alongside ceftobiprole. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Propofol14.6%6
2
Albuterol14.6%6
3
Furosemide14.6%6
4
Ticagrelor12.2%5
5
Linezolid12.2%5
6
Daptomycin4.9%2
7
Rifampin4.9%2
8
Cariprazine-hydrochloride2.4%1
9
Carbamazepine2.4%1
10
Diazepam2.4%1
11
Amphotericin-b2.4%1
12
Enoxaparin-sodium2.4%1
13
Amoxicillin2.4%1
14
Clavulanate-potassium2.4%1
15
Pantoprazole-sodium2.4%1

Taken alongside

1
Voriconazole17.1%7
2
Gabapentin14.6%6
3
Tizanidine-hydrochloride14.6%6
4
Linezolid14.6%6
5
Sufentanil-citrate14.6%6
6
Esomeprazole14.6%6
7
Insulin12.2%5
8
Duloxetine-hydrochloride9.8%4
9
Azithromycin9.8%4
10
Pantoprazole-sodium9.8%4
11
Aspirin7.3%3
12
Sodium-chloride7.3%3
13
Atorvastatin-calcium4.9%2
14
Potassium-chloride4.9%2
15
Rosuvastatin4.9%2

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ceftobiprole side effects

36.6% of ceftobiprole adverse event reports involve female patients and 46.3% involve male patients. The largest age group is elderly at 58%. These figures reflect who reports side effects, not underlying risk.

Sex

Female36.6%
Male46.3%
Unknown17.1%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6442.4%
65+57.6%

What is ceftobiprole used for

Conditions and purposes for which patients were taking ceftobiprole when the adverse event was reported.

BacteraemiaBacterial InfectionCoronary Artery DiseaseCystic FibrosisDevice Related InfectionEndocarditisEndocarditisInfectionMetapneumovirus PneumoniaPneumonia StaphylococcalProduct Used For Unknown IndicationPneumoniaPneumonia BacterialProduct Used For Unknown Indication

Ceftobiprole brand names and reporting trend

Ceftobiprole is sold under the brand name Zevtera.

Brand names

Zevtera20

Quarterly reports (20172025)

201720182025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ceftobiprole with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.