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Ceftizoxime Side Effects

The most commonly reported side effects of ceftizoxime include white blood cell count decreased, pyrexia, and rash, based on 215 FDA adverse event reports from 2004 to 2025. 2.8% of reports found the drug to be ineffective.

Ceftizoxime side effects

Percentages show how often each reaction appears relative to total reports for ceftizoxime.

1
White Blood Cell Count Decreased6.0%13
2
Pyrexia6.0%13
3
Rash5.6%12
4
Off Label Use5.6%12
5
Pneumonia4.7%10
6
Drug Interaction3.7%8
7
Hepatic Function Abnormal3.7%8
8
Pancytopenia3.7%8
9
Chills3.3%7
10
Platelet Count Decreased3.3%7
11
Pyrexia2.8%6
12
Drug Ineffective2.8%6
13
Liver Injury2.8%6
14
Interstitial Lung Disease2.8%6
15
Neutrophil Count Decreased2.8%6

These are voluntary reports and do not establish that ceftizoxime caused these reactions.

Report severity

95.3%Serious205 reports
40.9%Hospitalizations88 reports
17.2%Fatal37 reports

Seriousness is determined by the reporter, not by OpenClaim.

Ceftizoxime drug interactions

Other drugs that appear in adverse event reports alongside ceftizoxime. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Methylprednisolone6.0%13
2
Tacrolimus4.2%9
3
Dexamethasone4.2%9
4
Vancomycin4.2%9
5
Mycophenolate3.7%8
6
Celecoxib3.7%8
7
Methotrexate3.3%7
8
Prednisone3.3%7
9
Rituximab3.3%7
10
Cyclophosphamide3.3%7
11
Moxifloxacin-hydrochloride2.8%6
12
Azithromycin2.8%6
13
Amoxicillin2.8%6
14
Imipenem2.8%6
15
Venetoclax2.8%6

Taken alongside

1
Dexamethasone10.2%22
2
Sodium-chloride9.8%21
3
Methylprednisolone9.3%20
4
Levofloxacin8.4%18
5
Furosemide7.0%15
6
Acetaminophen6.5%14
7
Heparin6.0%13
8
Potassium-chloride6.0%13
9
Metoprolol5.6%12
10
Pantoprazole-sodium5.6%12
11
Esomeprazole5.6%12
12
Ibuprofen5.1%11
13
Omeprazole5.1%11
14
Insulin5.1%11
15
Aspirin5.1%11

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports ceftizoxime side effects

40.9% of ceftizoxime adverse event reports involve female patients and 54.0% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female40.9%
Male54.0%
Unknown5.1%

Age group

< 28.1%
2–114.6%
12–170.5%
18–6452.8%
65+34.0%

What is ceftizoxime used for

Conditions and purposes for which patients were taking ceftizoxime when the adverse event was reported.

Abdominal AbscessAnti-infective TherapyAntibiotic ProphylaxisAntibiotic TherapyAbdominal Pain UpperAdverse EventAnti-infective TherapyAntibiotic ProphylaxisAntibiotic TherapyAntiinflammatory TherapyAppendicitisBacterial InfectionBacterial SepsisBronchopneumoniaBronchitis

Showing 15 of 63 indications

Ceftizoxime brand names and reporting trend

Ceftizoxime is sold under the brand name Cefizox In Dextrose 5% In Plastic Container.

Brand names

Cefizox In Dextrose 5% In Plastic Container231

Quarterly reports (20042025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking ceftizoxime with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.