OpenClaim

Cefmetazole Side Effects

The most commonly reported side effects of cefmetazole include pyrexia, pneumonia, and off label use, based on 653 FDA adverse event reports from 2004 to 2025. 6.0% of reports found the drug to be ineffective.

Cefmetazole side effects

Percentages show how often each reaction appears relative to total reports for cefmetazole.

1
Pyrexia6.6%43
2
Drug Ineffective6.0%39
3
Pneumonia4.7%31
4
Off Label Use4.7%31
5
Anaemia3.7%24
6
Diarrhoea3.1%20
7
Renal Impairment2.9%19
8
Vomiting2.8%18
9
Urinary Tract Infection2.8%18
10
Condition Aggravated2.6%17
11
Sepsis2.5%16
12
Pruritus2.5%16
13
Exposure During Pregnancy2.3%15
14
Hepatic Function Abnormal2.3%15
15
Rash2.1%14

These are voluntary reports and do not establish that cefmetazole caused these reactions.

Report severity

96.8%Serious632 reports
59.3%Hospitalizations387 reports
22.2%Fatal145 reports

Seriousness is determined by the reporter, not by OpenClaim.

Cefmetazole drug interactions

Other drugs that appear in adverse event reports alongside cefmetazole. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Prednisolone7.0%46
2
Tacrolimus4.9%32
3
Meropenem3.5%23
4
Metronidazole3.4%22
5
Methylprednisolone3.2%21
6
Vancomycin2.8%18
7
Atezolizumab2.8%18
8
Prednisone2.6%17
9
Mesalamine2.5%16
10
Propofol2.5%16
11
Levofloxacin2.1%14
12
Paclitaxel2.1%14
13
Carboplatin2.0%13
14
Fentanyl1.8%12
15
Ciprofloxacin1.8%12

Taken alongside

1
Furosemide11.3%74
2
Meropenem9.2%60
3
Fentanyl8.9%58
4
Sodium-chloride8.7%57
5
Acetaminophen8.7%57
6
Dexamethasone8.3%54
7
Prednisolone8.0%52
8
Levofloxacin8.0%52
9
Omeprazole7.8%51
10
Magnesium-oxide7.7%50
11
Famotidine7.5%49
12
Lansoprazole6.6%43
13
Amlodipine6.1%40
14
Potassium-chloride5.5%36
15
Prednisone5.5%36

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports cefmetazole side effects

41.3% of cefmetazole adverse event reports involve female patients and 52.1% involve male patients. The largest age group is elderly at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female41.3%
Male52.1%
Unknown6.6%

Age group

< 22.9%
2–113.1%
12–172.1%
18–6439.6%
65+52.2%

What is cefmetazole used for

Conditions and purposes for which patients were taking cefmetazole when the adverse event was reported.

Alveolitis AllergicAnaesthesiaAnaesthesia ProcedureAnal AbscessAntibiotic ProphylaxisAntibiotic TherapyAppendicitisArthritisAmniotic Cavity InfectionAnti-infective TherapyAntibiotic TherapyAntiinflammatory TherapyAntipyresisBacteraemiaBehcet^s Syndrome

Showing 15 of 159 indications

Cefmetazole brand names and reporting trend

Cefmetazole is sold under the brand name Zefazone In Plastic Container.

Brand names

Zefazone In Plastic Container724

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking cefmetazole with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.