OpenClaim

Cefdinir Side Effects

The most commonly reported side effects of cefdinir include chronic kidney disease, diarrhoea, and pneumonia, based on 10,668 FDA adverse event reports from 2004 to 2025. 3.1% of reports found the drug to be ineffective.

Cefdinir side effects

Percentages show how often each reaction appears relative to total reports for cefdinir.

1
Chronic Kidney Disease5.2%556
2
Diarrhoea5.1%543
3
Pneumonia4.8%509
4
Fatigue4.7%497
5
Nausea4.1%436
6
Renal Failure3.9%414
7
Acute Kidney Injury3.8%401
8
Headache3.7%391
9
Sinusitis3.6%381
10
Pain3.6%380
11
Dyspnoea3.5%377
12
Drug Ineffective3.1%333
13
Urinary Tract Infection3.1%332
14
Off Label Use3.1%332
15
Death3.0%321

These are voluntary reports and do not establish that cefdinir caused these reactions.

Report severity

66.1%Serious7,050 reports
35.5%Hospitalizations3,789 reports
7.4%Fatal785 reports

Seriousness is determined by the reporter, not by OpenClaim.

Cefdinir drug interactions

Other drugs that appear in adverse event reports alongside cefdinir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Esomeprazole4.6%491
2
Lenalidomide4.5%480
3
Omeprazole4.4%467
4
Pantoprazole-sodium3.4%361
5
Sodium-oxybate2.9%308
6
Lansoprazole2.8%301
7
Dupilumab2.6%273
8
Etanercept1.5%165
9
Adalimumab1.5%165
10
Ethinyl-estradiol1.5%156
11
Drospirenone1.4%149
12
Dexlansoprazole1.3%143
13
Aspirin1.3%140
14
Amoxicillin1.3%135
15
Prednisone1.3%134

Taken alongside

1
Acetaminophen20.8%2,214
2
Albuterol17.3%1,846
3
Prednisone16.7%1,780
4
Aspirin14.6%1,554
5
Fluticasone14.3%1,521
6
Ergocalciferol13.2%1,412
7
Furosemide13.1%1,400
8
Ondansetron11.4%1,219
9
Azithromycin11.2%1,193
10
Gabapentin11.1%1,184
11
Levothyroxine-sodium10.9%1,160
12
Omeprazole10.9%1,158
13
Atorvastatin-calcium10.8%1,157
14
Amlodipine10.3%1,095
15
Amoxicillin10.0%1,064

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports cefdinir side effects

50.8% of cefdinir adverse event reports involve female patients and 40.9% involve male patients. The largest age group is adult at 44%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.8%
Male40.9%
Unknown8.3%

Age group

< 23.0%
2–117.9%
12–173.2%
18–6443.9%
65+41.9%

What is cefdinir used for

Conditions and purposes for which patients were taking cefdinir when the adverse event was reported.

Abdominal PainAbscessAbscess LimbAbscess Sweat GlandAcneActinomycosisAcute Myocardial InfarctionAcute SinusitisAcute TonsillitisAdenoidal HypertrophyAdverse EventAnalgesic Intervention Supportive TherapyAnalgesic TherapyAnti-infective TherapyAntibiotic Associated Colitis

Showing 15 of 434 indications

Cefdinir brand names and reporting trend

Cefdinir is sold under the brand name Omnicef.

Brand names

Omnicef8,014

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking cefdinir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.