OpenClaim

Casimersen Side Effects

The most commonly reported side effects of casimersen include product dose omission issue, no adverse event, and poor venous access, based on 834 FDA adverse event reports from 2019 to 2025.

Casimersen side effects

Percentages show how often each reaction appears relative to total reports for casimersen.

1
Product Dose Omission Issue31.1%259
2
No Adverse Event19.9%166
3
Poor Venous Access12.2%102
4
Device Issue9.1%76
5
Intentional Dose Omission8.9%74
6
Malaise4.3%36
7
Pyrexia3.8%32
8
Covid-193.6%30
9
Influenza2.3%19
10
Pneumonia2.0%17
11
Product Distribution Issue2.0%17
12
Dehydration1.8%15
13
Cough1.8%15
14
Fall1.8%15
15
Illness1.7%14

These are voluntary reports and do not establish that casimersen caused these reactions.

Report severity

16.8%Serious140 reports
12.6%Hospitalizations105 reports
1.0%Fatal8 reports

Seriousness is determined by the reporter, not by OpenClaim.

Casimersen drug interactions

Other drugs that appear in adverse event reports alongside casimersen. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Vamorolone5.8%48
2
Givinostat-hydrochloride0.6%5
3
Prednisone0.4%3
4
Eteplirsen0.2%2
5
Deflazacort0.2%2
6
Ciprofloxacin0.2%2
7
Adalimumab0.1%1
8
Golodirsen0.1%1
9
Escitalopram-oxalate0.1%1
10
Aspirin0.1%1

Taken alongside

1
Ergocalciferol17.3%144
2
Lisinopril16.1%134
3
Prednisone11.5%96
4
Deflazacort11.5%96
5
Famotidine6.1%51
6
Albuterol5.8%48
7
Spironolactone5.6%47
8
Carvedilol5.5%46
9
Calcium-carbonate4.9%41
10
Polyethylene-glycol-33504.8%40
11
Prednisolone4.1%34
12
Cholecalciferol3.8%32
13
Eplerenone3.5%29
14
Omeprazole3.4%28
15
Hydrocortisone3.0%25

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports casimersen side effects

0.5% of casimersen adverse event reports involve female patients and 98.6% involve male patients. The largest age group is adolescent at 38%. These figures reflect who reports side effects, not underlying risk.

Sex

Female0.5%
Male98.6%
Unknown1.0%

Age group

< 21.7%
2–1134.0%
12–1737.5%
18–6426.8%
65+0.0%

What is casimersen used for

Conditions and purposes for which patients were taking casimersen when the adverse event was reported.

Becker^s Muscular DystrophyDuchenne Muscular DystrophyDuchenne Muscular DystrophyMuscular DystrophyProduct Used For Unknown IndicationProduct Used For Unknown Indication

Casimersen brand names and reporting trend

Casimersen is sold under the brand name Amondys 45.

Brand names

Amondys 4541

Quarterly reports (20192025)

2019202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking casimersen with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.