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Carvedilol Side Effects

The most commonly reported side effects of carvedilol include fatigue, dyspnoea, and diarrhoea, based on 136,180 FDA adverse event reports from 2004 to 2025. 3.6% of reports found the drug to be ineffective.

Carvedilol side effects

Percentages show how often each reaction appears relative to total reports for carvedilol.

1
Fatigue5.5%7,501
2
Dyspnoea4.9%6,609
3
Diarrhoea4.5%6,070
4
Dizziness3.8%5,224
5
Nausea3.8%5,176
6
Death3.8%5,176
7
Drug Ineffective3.6%4,937
8
Hypotension3.4%4,622
9
Acute Kidney Injury3.3%4,468
10
Off Label Use3.2%4,365
11
Asthenia3.1%4,194
12
Chronic Kidney Disease3.0%4,043
13
Fall2.7%3,696
14
Headache2.6%3,559
15
Pain2.5%3,465

These are voluntary reports and do not establish that carvedilol caused these reactions.

Report severity

69.5%Serious94,638 reports
40.2%Hospitalizations54,766 reports
12.0%Fatal16,371 reports

Seriousness is determined by the reporter, not by OpenClaim.

Carvedilol drug interactions

Other drugs that appear in adverse event reports alongside carvedilol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Lenalidomide4.9%6,655
2
Valsartan4.9%6,644
3
Sacubitril4.1%5,613
4
Omeprazole2.8%3,769
5
Aspirin2.6%3,493
6
Esomeprazole2.5%3,443
7
Rivaroxaban2.4%3,210
8
Furosemide2.3%3,127
9
Apixaban2.3%3,094
10
Pantoprazole-sodium2.2%2,987
11
Adalimumab2.2%2,979
12
Dabigatran-etexilate-mesylate2.1%2,843
13
Amlodipine2.0%2,748
14
Rosiglitazone-maleate1.8%2,414
15
Atorvastatin-calcium1.7%2,383

Taken alongside

1
Aspirin29.3%39,967
2
Furosemide27.3%37,233
3
Atorvastatin-calcium20.0%27,234
4
Amlodipine16.6%22,586
5
Lisinopril16.2%22,068
6
Acetaminophen13.5%18,383
7
Ergocalciferol13.2%18,039
8
Levothyroxine-sodium13.1%17,798
9
Insulin12.2%16,641
10
Metformin11.4%15,556
11
Omeprazole11.3%15,418
12
Spironolactone11.0%14,978
13
Losartan-potassium10.7%14,607
14
Simvastatin9.7%13,204
15
Gabapentin9.7%13,153

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports carvedilol side effects

43.8% of carvedilol adverse event reports involve female patients and 49.9% involve male patients. The largest age group is elderly at 60%. These figures reflect who reports side effects, not underlying risk.

Sex

Female43.8%
Male49.9%
Unknown6.3%

Age group

< 20.2%
2–110.3%
12–170.3%
18–6439.2%
65+60.0%

What is carvedilol used for

Conditions and purposes for which patients were taking carvedilol when the adverse event was reported.

Abnormal BehaviourAccidental ExposureAccidental OverdoseAcute Coronary SyndromeAcute Kidney InjuryAcute Myocardial InfarctionAcute Pulmonary OedemaAdenocarcinoma Of ColonAdenovirus InfectionAdjuvant TherapyAdrenal Blockade TherapyAdrenal DisorderAdrenal InsufficiencyAdverse EventAge Indeterminate Myocardial Infarction

Showing 15 of 848 indications

Carvedilol brand names and reporting trend

Carvedilol is sold under brand names including Coreg, Carvedilol Phosphate.

Brand names

Coreg104,164
Carvedilol Phosphate298

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking carvedilol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.