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Carisoprodol Side Effects

The most commonly reported side effects of carisoprodol include pain, nausea, and fatigue, based on 30,860 FDA adverse event reports from 2004 to 2025. 4.4% of reports found the drug to be ineffective.

Carisoprodol side effects

Percentages show how often each reaction appears relative to total reports for carisoprodol.

1
Pain4.8%1,486
2
Drug Ineffective4.4%1,364
3
Nausea4.2%1,291
4
Fatigue3.9%1,214
5
Diarrhoea3.7%1,144
6
Headache3.4%1,060
7
Off Label Use3.4%1,046
8
Completed Suicide3.0%938
9
Toxicity To Various Agents3.0%921
10
Malaise2.9%890
11
Vomiting2.9%880
12
Completed Suicide2.7%837
13
Dyspnoea2.7%833
14
Death2.6%815
15
Fall2.5%780

These are voluntary reports and do not establish that carisoprodol caused these reactions.

Report severity

74.8%Serious23,070 reports
30.2%Hospitalizations9,326 reports
19.6%Fatal6,036 reports

Seriousness is determined by the reporter, not by OpenClaim.

Carisoprodol drug interactions

Other drugs that appear in adverse event reports alongside carisoprodol. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Acetaminophen8.1%2,485
2
Oxycodone7.6%2,342
3
Hydrocodone6.0%1,846
4
Alprazolam5.3%1,634
5
Fentanyl4.1%1,255
6
Adalimumab3.6%1,125
7
Pregabalin3.3%1,021
8
Sodium-oxybate2.9%895
9
Esomeprazole2.9%883
10
Omeprazole2.6%790
11
Tramadol-hydrochloride2.5%781
12
Diazepam2.5%759
13
Gabapentin2.3%699
14
Quetiapine-fumarate2.3%696
15
Morphine-sulfate2.0%628

Taken alongside

1
Acetaminophen21.9%6,764
2
Hydrocodone14.5%4,472
3
Oxycodone12.8%3,936
4
Gabapentin10.7%3,300
5
Alprazolam10.6%3,278
6
Aspirin8.9%2,751
7
Levothyroxine-sodium8.5%2,638
8
Ergocalciferol8.4%2,606
9
Albuterol8.4%2,591
10
Ibuprofen8.3%2,550
11
Omeprazole7.5%2,320
12
Furosemide7.1%2,183
13
Atorvastatin-calcium6.8%2,097
14
Zolpidem-tartrate6.8%2,093
15
Prednisone6.5%2,005

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports carisoprodol side effects

62.1% of carisoprodol adverse event reports involve female patients and 32.1% involve male patients. The largest age group is adult at 72%. These figures reflect who reports side effects, not underlying risk.

Sex

Female62.1%
Male32.1%
Unknown5.8%

Age group

< 20.4%
2–110.4%
12–170.8%
18–6472.4%
65+25.9%

What is carisoprodol used for

Conditions and purposes for which patients were taking carisoprodol when the adverse event was reported.

Abdominal DiscomfortAbdominal DistensionAbdominal HerniaAbdominal NeoplasmAbdominal PainAbdominal Pain UpperAccident At WorkAccidental ExposureAccidental Exposure To ProductAccidental Exposure To Product By ChildAccidental OverdoseAcromegalyAcute Coronary SyndromeAcute Myocardial InfarctionAcute Sinusitis

Showing 15 of 982 indications

Carisoprodol brand names and reporting trend

Carisoprodol is sold under the brand name Carisoprodol Compound.

Brand names

Carisoprodol Compound9,625

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking carisoprodol with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.