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Carboplatin Side Effects

The most commonly reported side effects of carboplatin include off label use, neutropenia, and anaemia, based on 131,142 FDA adverse event reports from 2004 to 2025. 3.1% of reports found the drug to be ineffective.

#1 Reported: Off Label UseAll side effects ↓Top Co-Medication: PaclitaxelDrug interactions ↓53% of Reports Are AdultDemographics ↓

Carboplatin side effects

Percentages show how often each reaction appears relative to total reports for carboplatin.

1
Off Label Use6.4%8,394
2
Neutropenia4.9%6,461
3
Anaemia4.9%6,406
4
Alopecia4.8%6,232
5
Nausea4.5%5,951
6
Febrile Neutropenia4.5%5,891
7
Disease Progression4.3%5,682
8
Malignant Neoplasm Progression4.3%5,589
9
Diarrhoea4.2%5,482
10
Thrombocytopenia4.0%5,291
11
Dyspnoea3.5%4,652
12
Vomiting3.2%4,168
13
Drug Ineffective3.1%4,100
14
Fatigue3.1%4,078
15
Pyrexia3.1%4,044

These are voluntary reports and do not establish that carboplatin caused these reactions.

Report severity

94.2%Serious123,573 reports
41.8%Hospitalizations54,860 reports
15.7%Fatal20,557 reports

Seriousness is determined by the reporter, not by OpenClaim.

Carboplatin drug interactions

Other drugs that appear in adverse event reports alongside carboplatin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Paclitaxel31.9%41,840
2
Etoposide14.3%18,750
3
Pembrolizumab13.7%17,982
4
Pemetrexed13.0%17,033
5
Bevacizumab12.3%16,085
6
Docetaxel10.0%13,149
7
Gemcitabine7.5%9,799
8
Atezolizumab6.6%8,702
9
Cyclophosphamide6.5%8,550
10
Doxorubicin-hydrochloride6.0%7,908
11
Trastuzumab5.5%7,263
12
Ifosfamide5.5%7,192
13
Cisplatin4.9%6,410
14
Vincristine-sulfate4.8%6,331
15
Rituximab3.8%5,008

Taken alongside

1
Dexamethasone8.9%11,718
2
Paclitaxel7.9%10,389
3
Ondansetron6.2%8,127
4
Acetaminophen5.0%6,577
5
Omeprazole3.0%3,979
6
Etoposide2.9%3,822
7
Pantoprazole-sodium2.9%3,817
8
Trastuzumab2.8%3,665
9
Docetaxel2.8%3,619
10
Folic-acid2.7%3,589
11
Pemetrexed2.7%3,517
12
Levothyroxine-sodium2.6%3,457
13
Aspirin2.6%3,430
14
Amlodipine2.3%3,039
15
Atorvastatin-calcium2.3%2,984

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports carboplatin side effects

52.8% of carboplatin adverse event reports involve female patients and 35.0% involve male patients. The largest age group is adult at 53%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.8%
Male35.0%
Unknown12.2%

Age group

< 21.5%
2–113.1%
12–170.9%
18–6452.7%
65+41.8%

What is carboplatin used for

Conditions and purposes for which patients were taking carboplatin when the adverse event was reported.

Abdominal LymphadenopathyAbdominal NeoplasmAbdominal Wall Neoplasm MalignantAccident At WorkAccidental ExposureAccidental Exposure To ProductAcinar Cell Carcinoma Of PancreasAcinic Cell Carcinoma Of Salivary GlandAcute LeukaemiaAcute Lymphocytic LeukaemiaAcute Lymphocytic Leukaemia RecurrentAcute Myeloid LeukaemiaAcute Promyelocytic LeukaemiaAdenocarcinomaAdenocarcinoma Gastric

Showing 15 of 2,111 indications

Carboplatin brand names and reporting trend

Carboplatin is sold under the brand name Paraplatin.

Brand names

Paraplatin151,487

Quarterly reports (2004–2025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking carboplatin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

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