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Capivasertib Side Effects

The most commonly reported side effects of capivasertib include diarrhoea, rash, and death, based on 2,056 FDA adverse event reports from 2020 to 2025.

Capivasertib side effects

Percentages show how often each reaction appears relative to total reports for capivasertib.

1
Diarrhoea16.0%328
2
Rash14.6%301
3
Death14.2%291
4
Hyperglycaemia9.8%201
5
Nausea5.6%115
6
Disease Progression4.7%97
7
Vomiting4.5%92
8
Fatigue4.4%90
9
Malignant Neoplasm Progression4.2%86
10
Blood Glucose Increased3.8%79
11
Pyrexia3.1%64
12
Diabetic Ketoacidosis2.9%60
13
Decreased Appetite2.8%58
14
Urinary Tract Infection2.6%53
15
Dehydration2.6%53

These are voluntary reports and do not establish that capivasertib caused these reactions.

Report severity

80.8%Serious1,661 reports
27.3%Hospitalizations561 reports
18.0%Fatal370 reports

Seriousness is determined by the reporter, not by OpenClaim.

Capivasertib drug interactions

Other drugs that appear in adverse event reports alongside capivasertib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Fulvestrant23.6%486
2
Elacestrant-hydrochloride1.2%24
3
Trastuzumab0.9%19
4
Olaparib0.8%16
5
Palbociclib0.7%14
6
Ribociclib0.6%13
7
Abemaciclib0.5%10
8
Abiraterone-acetate0.4%9
9
Hydrocortisone0.3%7
10
Letrozole0.3%7
11
Tamoxifen-citrate0.3%7
12
Propranolol-hydrochloride0.3%6
13
Anastrozole0.2%5
14
Goserelin0.2%4
15
Prednisone0.1%3

Taken alongside

1
Fulvestrant6.3%130
2
Ondansetron4.0%82
3
Loperamide-hydrochloride3.5%71
4
Acetaminophen3.4%70
5
Ergocalciferol3.4%70
6
Denosumab2.7%55
7
Levothyroxine-sodium2.6%53
8
Apixaban2.5%52
9
Pantoprazole-sodium2.2%45
10
Metformin2.1%44
11
Prochlorperazine2.0%41
12
Oxycodone1.9%40
13
Dexamethasone1.9%39
14
Furosemide1.8%37
15
Cetirizine-hydrochloride1.8%37

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports capivasertib side effects

89.2% of capivasertib adverse event reports involve female patients and 2.4% involve male patients. The largest age group is elderly at 56%. These figures reflect who reports side effects, not underlying risk.

Sex

Female89.2%
Male2.4%
Unknown8.5%

Age group

< 20.0%
2–110.0%
12–170.1%
18–6443.9%
65+56.0%

What is capivasertib used for

Conditions and purposes for which patients were taking capivasertib when the adverse event was reported.

Adverse Drug ReactionAgranulocytosisAntibiotic ProphylaxisBreast CancerBenign Breast NeoplasmBone CancerBone NeoplasmBreast CancerBreast Cancer FemaleBreast Cancer MaleBreast Cancer MetastaticBreast Cancer RecurrentBreast Cancer Stage IBreast Cancer Stage IiBreast Cancer Stage Iv

Showing 15 of 69 indications

Capivasertib brand names and reporting trend

Capivasertib is sold under the brand name Truqap.

Brand names

Truqap990

Quarterly reports (20202025)

2020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking capivasertib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.