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Cangrelor Side Effects

The most commonly reported side effects of cangrelor include off label use, vascular stent thrombosis, and haemorrhage, based on 428 FDA adverse event reports from 2006 to 2025. 7.0% of reports found the drug to be ineffective.

Cangrelor side effects

Percentages show how often each reaction appears relative to total reports for cangrelor.

1
Off Label Use37.1%159
2
Vascular Stent Thrombosis9.6%41
3
Drug Ineffective7.0%30
4
Haemorrhage6.3%27
5
Death4.9%21
6
Cardiac Arrest4.7%20
7
No Adverse Event4.4%19
8
Inappropriate Schedule Of Product Administration4.2%18
9
Cardiogenic Shock3.5%15
10
Labelled Drug-drug Interaction Medication Error3.3%14
11
Thrombocytopenia3.3%14
12
Gastrointestinal Haemorrhage3.3%14
13
Eosinophilia3.3%14
14
Hypotension3.0%13
15
Dyspnoea2.8%12

These are voluntary reports and do not establish that cangrelor caused these reactions.

Report severity

75.0%Serious321 reports
25.9%Hospitalizations111 reports
19.4%Fatal83 reports

Seriousness is determined by the reporter, not by OpenClaim.

Cangrelor drug interactions

Other drugs that appear in adverse event reports alongside cangrelor. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Heparin14.3%61
2
Ticagrelor14.3%61
3
Aspirin14.0%60
4
Gemfibrozil7.7%33
5
Bivalirudin5.6%24
6
Clopidogrel-bisulfate4.7%20
7
Eptifibatide4.0%17
8
Tirofiban-hydrochloride3.3%14
9
Prasugrel-hydrochloride3.0%13
10
Enoxaparin-sodium2.6%11
11
Fentanyl2.3%10
12
Warfarin2.1%9
13
Atorvastatin-calcium1.9%8
14
Amiodarone-hydrochloride1.9%8
15
Metoprolol1.6%7

Taken alongside

1
Aspirin21.3%91
2
Heparin19.6%84
3
Ticagrelor12.1%52
4
Gemfibrozil8.9%38
5
Fentanyl7.0%30
6
Atorvastatin-calcium5.6%24
7
Nitroglycerin4.9%21
8
Furosemide4.7%20
9
Eptifibatide4.2%18
10
Metoprolol4.0%17
11
Pantoprazole-sodium3.7%16
12
Acetaminophen3.7%16
13
Bivalirudin3.7%16
14
Midazolam3.3%14
15
Ondansetron2.8%12

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports cangrelor side effects

23.4% of cangrelor adverse event reports involve female patients and 38.1% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female23.4%
Male38.1%
Unknown38.6%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6451.4%
65+48.6%

What is cangrelor used for

Conditions and purposes for which patients were taking cangrelor when the adverse event was reported.

Acute Myocardial InfarctionAngina UnstableAngioplastyAnticoagulant TherapyAntiplatelet TherapyAortic Aneurysm RepairAcute Coronary SyndromeAcute Myocardial InfarctionAneurysm RupturedAngiogram CerebralAnticoagulant TherapyAntiplatelet TherapyAortic Valve ReplacementBrain Stent InsertionBrain Stent Insertion

Showing 15 of 72 indications

Cangrelor brand names and reporting trend

Cangrelor is sold under the brand name Cangrelor.

Brand names

Cangrelor274

Quarterly reports (20062025)

2006201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking cangrelor with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.