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Calcium Chloride Side Effects

The most commonly reported side effects of calcium chloride include death, death, and peritonitis, based on 48,017 FDA adverse event reports from 2004 to 2025.

Calcium Chloride side effects

Percentages show how often each reaction appears relative to total reports for calcium chloride.

1
Death7.6%3,648
2
Death7.4%3,571
3
Peritonitis3.6%1,714
4
Peritonitis Bacterial3.1%1,501
5
Myocardial Infarction3.0%1,460
6
Cardiac Arrest2.7%1,278
7
Peritonitis2.5%1,223
8
Pneumonia2.3%1,111
9
Sepsis2.2%1,052
10
Peritonitis Bacterial2.1%1,030
11
Cardiac Failure2.1%1,011
12
Cardiac Disorder1.9%913
13
Cerebrovascular Accident1.9%908
14
Peritoneal Dialysis Complication1.8%862
15
Dyspnoea1.8%854

These are voluntary reports and do not establish that calcium chloride caused these reactions.

Report severity

88.8%Serious42,624 reports
46.2%Hospitalizations22,186 reports
33.8%Fatal16,233 reports

Seriousness is determined by the reporter, not by OpenClaim.

Calcium Chloride drug interactions

Other drugs that appear in adverse event reports alongside calcium chloride. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-chloride88.4%42,425
2
Magnesium-chloride86.9%41,726
3
Dextrose85.3%40,962
4
Sodium-lactate84.0%40,328
5
Icodextrin11.5%5,538
6
Potassium-chloride5.5%2,650
7
Sodium-acetate3.6%1,733
8
Sodium-citrate2.6%1,269
9
Magnesium-sulfate1.2%569
10
Sodium-bicarbonate1.1%515
11
Hydrocortisone1.0%480
12
Acetaminophen1.0%462
13
Amino-acids0.9%454
14
Sodium-glycerophosphate0.9%449
15
Epinephrine0.9%430

Taken alongside

1
Potassium-chloride5.4%2,615
2
Sodium-chloride5.1%2,427
3
Dextrose3.3%1,587
4
Magnesium-chloride3.0%1,449
5
Sodium-acetate3.0%1,437
6
Insulin2.9%1,402
7
Acetaminophen2.9%1,394
8
Furosemide2.9%1,391
9
Aspirin2.5%1,181
10
Pantoprazole-sodium2.2%1,052
11
Heparin2.0%940
12
Ergocalciferol1.8%877
13
Amlodipine1.8%868
14
Magnesium-sulfate1.8%866
15
Sodium-lactate1.7%832

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports calcium chloride side effects

44.1% of calcium chloride adverse event reports involve female patients and 50.7% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female44.1%
Male50.7%
Unknown5.1%

Age group

< 21.2%
2–111.2%
12–171.1%
18–6451.1%
65+45.3%

What is calcium chloride used for

Conditions and purposes for which patients were taking calcium chloride when the adverse event was reported.

Abdominal DistensionAbdominal PainAccidental ExposureAccidental Exposure To ProductAccidental OverdoseAcidosisAcneAcute Kidney InjuryAcute Lymphocytic LeukaemiaAddison^s DiseaseAdenocarcinoma Of ColonAdjuvant TherapyAdverse EventAnaesthesiaAnaesthesia Procedure

Showing 15 of 535 indications

Calcium Chloride brand names and reporting trend

Calcium Chloride is sold under the brand name Dianeal Pd-1 W/ Dextrose 4.25% In Plastic Container.

Brand names

Dianeal Pd-1 W/ Dextrose 4.25% In Plastic Container3,853

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking calcium chloride with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.