OpenClaim

Calcipotriene Side Effects

The most commonly reported side effects of calcipotriene include psoriasis, nausea, and pain, based on 8,858 FDA adverse event reports from 2004 to 2025. 14.8% of reports found the drug to be ineffective.

Calcipotriene side effects

Percentages show how often each reaction appears relative to total reports for calcipotriene.

1
Psoriasis21.8%1,930
2
Drug Ineffective14.8%1,309
3
Nausea7.1%627
4
Pain6.9%610
5
Headache6.9%609
6
Diarrhoea6.2%553
7
Fatigue5.9%527
8
Pruritus5.7%505
9
Malaise4.8%425
10
Skin Exfoliation4.6%409
11
Nasopharyngitis4.6%405
12
Arthralgia4.6%404
13
Psoriatic Arthropathy4.3%384
14
Rash4.1%364
15
Vomiting4.1%360

These are voluntary reports and do not establish that calcipotriene caused these reactions.

Report severity

54.3%Serious4,810 reports
20.8%Hospitalizations1,846 reports
3.0%Fatal267 reports

Seriousness is determined by the reporter, not by OpenClaim.

Calcipotriene drug interactions

Other drugs that appear in adverse event reports alongside calcipotriene. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Apremilast18.6%1,646
2
Secukinumab18.0%1,594
3
Methotrexate11.1%982
4
Adalimumab10.3%910
5
Betamethasone8.6%758
6
Clobetasol-propionate6.9%614
7
Etanercept6.9%608
8
Triamcinolone4.1%362
9
Cyclosporine4.0%358
10
Ustekinumab4.0%355
11
Metformin3.7%330
12
Atorvastatin-calcium3.0%270
13
Prednisone3.0%263
14
Hydrochlorothiazide2.9%261
15
Amlodipine2.9%259

Taken alongside

1
Betamethasone40.9%3,621
2
Clobetasol-propionate20.7%1,833
3
Acetaminophen11.6%1,024
4
Aspirin10.8%958
5
Levothyroxine-sodium10.4%923
6
Ergocalciferol9.5%844
7
Metformin8.6%758
8
Triamcinolone8.4%747
9
Methotrexate8.3%737
10
Atorvastatin-calcium8.2%722
11
Omeprazole8.0%707
12
Amlodipine7.4%657
13
Albuterol7.2%638
14
Folic-acid6.5%580
15
Hydrochlorothiazide6.5%579

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports calcipotriene side effects

52.4% of calcipotriene adverse event reports involve female patients and 42.4% involve male patients. The largest age group is adult at 70%. These figures reflect who reports side effects, not underlying risk.

Sex

Female52.4%
Male42.4%
Unknown5.2%

Age group

< 20.1%
2–110.4%
12–170.7%
18–6470.2%
65+28.6%

What is calcipotriene used for

Conditions and purposes for which patients were taking calcipotriene when the adverse event was reported.

Abdominal Pain UpperActinic KeratosisAlopeciaAnkylosing SpondylitisAnxietyArthralgiaArthritisAcquired Blaschkoid DermatitisActinic KeratosisAcute Graft Versus Host DiseaseAcute Myeloid LeukaemiaAdverse Drug ReactionAllergy To AnimalAlopeciaAnkylosing Spondylitis

Showing 15 of 198 indications

Calcipotriene brand names and reporting trend

Calcipotriene is sold under the brand name Taclonex.

Brand names

Taclonex3,745

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking calcipotriene with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.