OpenClaim

Butenafine Side Effects

The most commonly reported side effects of butenafine include off label use, product use issue, and product use in unapproved indication, based on 1,183 FDA adverse event reports from 2004 to 2025. 25.0% of reports found the drug to be ineffective.

#1 Reported: Off Label UseAll side effects ↓Top Co-Medication: ClotrimazoleDrug interactions ↓51% of Reports Are AdultDemographics ↓

Butenafine side effects

Percentages show how often each reaction appears relative to total reports for butenafine.

1
Drug Ineffective25.0%296
2
Off Label Use10.8%128
3
Product Use Issue10.2%121
4
Product Use In Unapproved Indication8.3%98
5
Pruritus3.9%46
6
Rash3.3%39
7
Burning Sensation2.9%34
8
Condition Aggravated2.9%34
9
Drug Ineffective For Unapproved Indication2.6%31
10
Erythema2.6%31
11
Drug Effective For Unapproved Indication2.6%31
12
Therapeutic Response Unexpected2.5%30
13
Product Administered At Inappropriate Site2.2%26
14
Product Prescribing Issue2.0%24
15
Expired Product Administered1.9%23

These are voluntary reports and do not establish that butenafine caused these reactions.

Report severity

19.0%Serious225 reports
9.8%Hospitalizations116 reports
2.3%Fatal27 reports

Seriousness is determined by the reporter, not by OpenClaim.

Butenafine drug interactions

Other drugs that appear in adverse event reports alongside butenafine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Clotrimazole4.8%57
2
Lenalidomide1.1%13
3
Terbinafine1.0%12
4
Pregabalin0.8%9
5
Peginterferon0.7%8
6
Ribavirin0.7%8
7
Paclitaxel0.6%7
8
Bevacizumab0.6%7
9
Sodium-oxybate0.6%7
10
Carboplatin0.5%6
11
Emtricitabine0.5%6
12
Tenofovir0.5%6
13
Ritonavir0.5%6
14
Fosamprenavir-calcium0.5%6
15
Aripiprazole0.5%6

Taken alongside

1
Aspirin5.2%62
2
Acetaminophen4.6%55
3
Ergocalciferol4.2%50
4
Levothyroxine-sodium4.0%47
5
Furosemide3.9%46
6
Metformin3.3%39
7
Gabapentin3.3%39
8
Omeprazole2.9%34
9
Atorvastatin-calcium2.8%33
10
Insulin2.7%32
11
Lisinopril2.6%31
12
Oxycodone2.6%31
13
Hydrochlorothiazide2.5%30
14
Albuterol2.5%30
15
Ibuprofen2.5%30

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports butenafine side effects

40.9% of butenafine adverse event reports involve female patients and 47.0% involve male patients. The largest age group is adult at 51%. These figures reflect who reports side effects, not underlying risk.

Sex

Female40.9%
Male47.0%
Unknown12.1%

Age group

< 21.4%
2–112.8%
12–171.4%
18–6450.9%
65+43.5%

What is butenafine used for

Conditions and purposes for which patients were taking butenafine when the adverse event was reported.

AnaemiaAnal PruritusAngular CheilitisAntifungal ProphylaxisAntifungal TreatmentAphthous UlcerArthropod BiteAcne PustularAngular CheilitisAntifungal ProphylaxisAntifungal TreatmentBalanoposthitisBalanoposthitis InfectiveBurning SensationBacterial Infection

Showing 15 of 134 indications

Butenafine brand names and reporting trend

Butenafine is sold under the brand name Mentax-tc.

Brand names

Mentax-tc1

Quarterly reports (2004–2025)

2005201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking butenafine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.

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