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Brompheniramine Side Effects

The most commonly reported side effects of brompheniramine include fatigue, chronic kidney disease, and pain, based on 512 FDA adverse event reports from 2004 to 2025.

Brompheniramine side effects

Percentages show how often each reaction appears relative to total reports for brompheniramine.

1
Fatigue5.1%26
2
Chronic Kidney Disease4.5%23
3
Pain4.1%21
4
Headache3.9%20
5
Completed Suicide3.7%19
6
Acute Kidney Injury3.5%18
7
Off Label Use3.5%18
8
Death3.3%17
9
Fall3.3%17
10
Renal Failure3.3%17
11
Toxicity To Various Agents3.1%16
12
Pneumonia3.1%16
13
Cough3.1%16
14
Anxiety2.9%15
15
Nausea2.9%15

These are voluntary reports and do not establish that brompheniramine caused these reactions.

Report severity

67.0%Serious343 reports
31.1%Hospitalizations159 reports
16.0%Fatal82 reports

Seriousness is determined by the reporter, not by OpenClaim.

Brompheniramine drug interactions

Other drugs that appear in adverse event reports alongside brompheniramine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate9.6%49
2
Dextromethorphan9.0%46
3
Pseudoephedrine7.4%38
4
Acetaminophen6.6%34
5
Oxycodone6.1%31
6
Dupilumab5.9%30
7
Ibuprofen5.7%29
8
Lenalidomide5.3%27
9
Gabapentin4.9%25
10
Diphenhydramine4.7%24
11
Esomeprazole4.7%24
12
Omeprazole4.5%23
13
Citalopram-hydrobromide4.1%21
14
Hydromorphone-hydrochloride3.7%19
15
Celecoxib3.5%18

Taken alongside

1
Pseudoephedrine31.4%161
2
Dextromethorphan29.9%153
3
Albuterol21.7%111
4
Acetaminophen21.5%110
5
Fluticasone18.4%94
6
Ibuprofen15.6%80
7
Prednisone14.8%76
8
Ergocalciferol14.5%74
9
Azithromycin13.3%68
10
Amoxicillin13.3%68
11
Aspirin12.1%62
12
Omeprazole11.7%60
13
Ondansetron11.5%59
14
Gabapentin11.1%57
15
Montelukast-sodium10.0%51

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports brompheniramine side effects

59.4% of brompheniramine adverse event reports involve female patients and 34.8% involve male patients. The largest age group is adult at 57%. These figures reflect who reports side effects, not underlying risk.

Sex

Female59.4%
Male34.8%
Unknown5.9%

Age group

< 26.2%
2–117.6%
12–174.9%
18–6456.9%
65+24.4%

What is brompheniramine used for

Conditions and purposes for which patients were taking brompheniramine when the adverse event was reported.

Accidental Exposure To ProductAntiallergic TherapyAntitussive TherapyAsthmaAntiallergic TherapyAntitussive TherapyBronchitisBronchitisChest DiscomfortCoughCoughDrug TherapyDrug Use For Unknown IndicationDysphoniaDyspnoea

Showing 15 of 53 indications

Brompheniramine brand names and reporting trend

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking brompheniramine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.