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Brolucizumab Side Effects

The most commonly reported side effects of brolucizumab include visual impairment, vitreous floaters, and vision blurred, based on 3,565 FDA adverse event reports from 2019 to 2025. 6.1% of reports found the drug to be ineffective.

Brolucizumab side effects

Percentages show how often each reaction appears relative to total reports for brolucizumab.

1
Visual Impairment15.9%566
2
Vitreous Floaters15.6%555
3
Vision Blurred14.8%526
4
Eye Inflammation12.5%444
5
Visual Acuity Reduced11.9%424
6
Retinal Vasculitis10.7%381
7
Uveitis10.1%360
8
Vitritis9.9%354
9
Eye Pain8.8%315
10
Blindness6.8%243
11
Anterior Chamber Cell6.4%227
12
Vitreous Opacities6.2%221
13
Ocular Hyperaemia6.1%219
14
Drug Ineffective6.1%218
15
Keratic Precipitates5.9%211

These are voluntary reports and do not establish that brolucizumab caused these reactions.

Report severity

78.5%Serious2,797 reports
7.7%Hospitalizations276 reports
6.8%Fatal241 reports

Seriousness is determined by the reporter, not by OpenClaim.

Brolucizumab drug interactions

Other drugs that appear in adverse event reports alongside brolucizumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Aflibercept8.2%293
2
Ranibizumab8.0%284
3
Bevacizumab3.2%114
4
Faricimab-svoa0.8%29
5
Leucovorin-calcium0.7%25
6
Fluorouracil0.7%25
7
Irinotecan-hydrochloride0.7%25
8
Prednisone0.5%19
9
Budesonide0.4%16
10
Doxycycline0.4%16
11
Levofloxacin0.4%16
12
Albuterol0.4%16
13
Tiotropium-bromide0.4%16
14
Ipratropium-bromide0.4%16
15
Alendronate-sodium0.4%16

Taken alongside

1
Aflibercept2.4%86
2
Aspirin2.2%79
3
Amlodipine1.7%62
4
Atorvastatin-calcium1.5%53
5
Levothyroxine-sodium1.3%47
6
Metformin1.1%39
7
Moxifloxacin-hydrochloride1.0%37
8
Bisoprolol-fumarate1.0%36
9
Levofloxacin1.0%36
10
Metoprolol1.0%34
11
Omeprazole0.9%33
12
Losartan-potassium0.8%30
13
Ergocalciferol0.8%30
14
Lisinopril0.8%28
15
Bevacizumab0.8%28

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports brolucizumab side effects

50.1% of brolucizumab adverse event reports involve female patients and 35.7% involve male patients. The largest age group is elderly at 84%. These figures reflect who reports side effects, not underlying risk.

Sex

Female50.1%
Male35.7%
Unknown14.2%

Age group

< 20.0%
2–11<0.1%
12–17<0.1%
18–6415.6%
65+84.3%

What is brolucizumab used for

Conditions and purposes for which patients were taking brolucizumab when the adverse event was reported.

Age-related Macular DegenerationAneurysmAge-related Macular DegenerationAngiopathyAntiangiogenic TherapyCataract OperationChoroidal NeovascularisationCystoid Macular OedemaCentral Serous ChorioretinopathyChorioretinitisChorioretinopathyChoroidal NeovascularisationCongenital Eye DisorderCystoid Macular OedemaDetachment Of Retinal Pigment Epithelium

Showing 15 of 69 indications

Brolucizumab brand names and reporting trend

Brolucizumab is sold under the brand name Beovu.

Brand names

Beovu955

Quarterly reports (20192025)

2020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking brolucizumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.