OpenClaim

Brensocatib Side Effects

The most commonly reported side effects of brensocatib include cough, headache, and dyspnoea, based on 258 FDA adverse event reports from 2024 to 2025. 6.2% of reports found the drug to be ineffective.

Brensocatib side effects

Percentages show how often each reaction appears relative to total reports for brensocatib.

1
Cough12.4%32
2
Headache12.0%31
3
Dyspnoea11.6%30
4
Off Label Use9.3%24
5
Rash7.8%20
6
Fatigue7.0%18
7
Hypertension7.0%18
8
Therapy Interrupted6.6%17
9
Pneumonia6.2%16
10
Product Dose Omission Issue6.2%16
11
Drug Ineffective6.2%16
12
Adverse Drug Reaction5.8%15
13
Productive Cough5.8%15
14
Dizziness5.4%14
15
Infective Exacerbation Of Bronchiectasis5.0%13

These are voluntary reports and do not establish that brensocatib caused these reactions.

Report severity

45.7%Serious118 reports
17.1%Hospitalizations44 reports
2.3%Fatal6 reports

Seriousness is determined by the reporter, not by OpenClaim.

Brensocatib drug interactions

Other drugs that appear in adverse event reports alongside brensocatib. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Amikacin-sulfate9.3%24
2
Prednisone0.8%2
3
Acetaminophen0.8%2
4
Perindopril0.8%2
5
Prednisolone0.8%2
6
Beclomethasone0.8%2
7
Elexacaftor-ivacaftor-tezacaftor0.8%2
8
Ivacaftor0.8%2
9
Tobramycin0.8%2
10
Golimumab0.4%1
11
Albuterol0.4%1
12
Ipratropium-bromide0.4%1
13
Aztreonam0.4%1
14
Levofloxacin0.4%1
15
Minocycline-hydrochloride0.4%1

Taken alongside

1
Albuterol23.3%60
2
Fluticasone13.2%34
3
Sodium-chloride12.8%33
4
Azithromycin10.5%27
5
Budesonide10.1%26
6
Atorvastatin-calcium9.7%25
7
Vilanterol-trifenatate9.3%24
8
Umeclidinium-bromide8.9%23
9
Metoprolol7.8%20
10
Montelukast-sodium7.4%19
11
Formoterol6.6%17
12
Cholecalciferol6.6%17
13
Levothyroxine-sodium6.2%16
14
Acetaminophen6.2%16
15
Omeprazole5.8%15

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports brensocatib side effects

63.2% of brensocatib adverse event reports involve female patients and 20.9% involve male patients. The largest age group is elderly at 77%. These figures reflect who reports side effects, not underlying risk.

Sex

Female63.2%
Male20.9%
Unknown15.9%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6423.2%
65+76.8%

What is brensocatib used for

Conditions and purposes for which patients were taking brensocatib when the adverse event was reported.

AsthmaBacterial Disease CarrierBacterial InfectionBronchiectasisChronic Obstructive Pulmonary DiseaseChronic SinusitisCystic FibrosisCystic Fibrosis LungHeterotaxiaInfective Exacerbation Of BronchiectasisLower Respiratory Tract InfectionLung DisorderPneumoconiosisProduct Used For Unknown IndicationPulmonary Fibrosis

Brensocatib brand names and reporting trend

Brensocatib is sold under the brand name Brinsupri.

Brand names

Brinsupri13

Quarterly reports (20242025)

20242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking brensocatib with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.