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Boceprevir Side Effects

The most commonly reported side effects of boceprevir include fatigue, anaemia, and nausea, based on 9,317 FDA adverse event reports from 2008 to 2025.

Boceprevir side effects

Percentages show how often each reaction appears relative to total reports for boceprevir.

1
Fatigue19.3%1,802
2
Anaemia18.6%1,734
3
Nausea14.0%1,304
4
Dysgeusia9.7%902
5
Headache8.3%769
6
Rash8.1%755
7
White Blood Cell Count Decreased7.6%705
8
Vomiting7.4%691
9
Asthenia7.4%685
10
Decreased Appetite6.8%634
11
Weight Decreased6.6%617
12
Diarrhoea6.4%599
13
Dyspnoea6.3%583
14
Pyrexia5.7%528
15
Pruritus5.6%522

These are voluntary reports and do not establish that boceprevir caused these reactions.

Report severity

47.6%Serious4,435 reports
22.8%Hospitalizations2,124 reports
3.7%Fatal347 reports

Seriousness is determined by the reporter, not by OpenClaim.

Boceprevir drug interactions

Other drugs that appear in adverse event reports alongside boceprevir. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Ribavirin78.1%7,278
2
Peginterferon68.0%6,331
3
Telaprevir2.7%251
4
Ropeginterferon-alfa-2b-njft1.5%138
5
Sofosbuvir0.7%63
6
Tacrolimus0.4%38
7
Raltegravir-potassium0.4%33
8
Interferon0.3%31
9
Tenofovir0.3%31
10
Cyclosporine0.3%30
11
Filgrastim0.3%25
12
Ibuprofen0.2%23
13
Simeprevir-sodium0.2%23
14
Daclatasvir-dihydrochloride0.2%23
15
Mycophenolate0.2%21

Taken alongside

1
Peginterferon4.8%450
2
Ribavirin3.8%350
3
Omeprazole3.3%306
4
Acetaminophen3.2%297
5
Lisinopril2.6%242
6
Epoetin2.4%227
7
Ibuprofen2.3%210
8
Metformin2.1%192
9
Aspirin2.0%183
10
Levothyroxine-sodium1.8%172
11
Citalopram-hydrobromide1.8%171
12
Amlodipine1.7%163
13
Insulin1.7%160
14
Filgrastim1.7%158
15
Hydrochlorothiazide1.6%149

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports boceprevir side effects

38.6% of boceprevir adverse event reports involve female patients and 53.9% involve male patients. The largest age group is adult at 89%. These figures reflect who reports side effects, not underlying risk.

Sex

Female38.6%
Male53.9%
Unknown7.5%

Age group

< 2<0.1%
2–11<0.1%
12–17<0.1%
18–6489.4%
65+10.4%

What is boceprevir used for

Conditions and purposes for which patients were taking boceprevir when the adverse event was reported.

Acute Hepatitis CAnaemiaAntiviral ProphylaxisAntiviral TreatmentAnaemiaBenign Prostatic HyperplasiaBiliary CirrhosisChronic HepatitisChronic Hepatitis BChronic Hepatitis CComaComa HepaticCryoglobulinaemiaChronic Hepatitis CDisease Recurrence

Showing 15 of 52 indications

Boceprevir brand names and reporting trend

Boceprevir is sold under the brand name Victrelis.

Brand names

Victrelis2,151

Quarterly reports (20082025)

2010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking boceprevir with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.