OpenClaim

Besifloxacin Side Effects

The most commonly reported side effects of besifloxacin include eye pain, off label use, and vision blurred, based on 1,072 FDA adverse event reports from 2008 to 2025. 3.8% of reports found the drug to be ineffective.

Besifloxacin side effects

Percentages show how often each reaction appears relative to total reports for besifloxacin.

1
Eye Pain9.3%100
2
Off Label Use9.0%97
3
Vision Blurred8.1%87
4
Eye Irritation6.9%74
5
Hypersensitivity6.4%69
6
Cardiac Disorder4.7%50
7
Ocular Hyperaemia4.5%48
8
Chronic Kidney Disease4.1%44
9
Drug Ineffective3.8%41
10
Photophobia3.4%36
11
Foreign Body Sensation In Eyes3.1%33
12
Fatigue2.8%30
13
Renal Failure2.8%30
14
Impaired Healing2.7%29
15
Eye Swelling2.6%28

These are voluntary reports and do not establish that besifloxacin caused these reactions.

Report severity

42.6%Serious457 reports
16.0%Hospitalizations171 reports
6.5%Fatal70 reports

Seriousness is determined by the reporter, not by OpenClaim.

Besifloxacin drug interactions

Other drugs that appear in adverse event reports alongside besifloxacin. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Bromfenac-sodium8.0%86
2
Prednisolone7.5%80
3
Loteprednol-etabonate7.3%78
4
Epinephrine6.4%69
5
Moxifloxacin-hydrochloride6.3%67
6
Cenegermin-bkbj6.2%66
7
Tadalafil6.0%64
8
Prednisone6.0%64
9
Mometasone-furoate6.0%64
10
Olopatadine-hydrochloride6.0%64
11
Amlodipine6.0%64
12
Betaxolol-hydrochloride5.9%63
13
Lenalidomide4.8%51
14
Cyclophosphamide4.4%47
15
Chlorambucil4.3%46

Taken alongside

1
Difluprednate14.5%155
2
Prednisolone13.5%145
3
Bromfenac-sodium13.4%144
4
Acetaminophen11.0%118
5
Aspirin10.1%108
6
Loteprednol-etabonate10.0%107
7
Ergocalciferol10.0%107
8
Levothyroxine-sodium9.0%96
9
Gabapentin8.7%93
10
Nepafenac8.4%90
11
Prednisone8.3%89
12
Losartan-potassium8.1%87
13
Amlodipine8.0%86
14
Atorvastatin-calcium7.7%83
15
Fluticasone7.3%78

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports besifloxacin side effects

58.0% of besifloxacin adverse event reports involve female patients and 36.7% involve male patients. The largest age group is elderly at 52%. These figures reflect who reports side effects, not underlying risk.

Sex

Female58.0%
Male36.7%
Unknown5.3%

Age group

< 20.0%
2–111.0%
12–170.5%
18–6446.6%
65+51.8%

What is besifloxacin used for

Conditions and purposes for which patients were taking besifloxacin when the adverse event was reported.

Adverse EventAntibiotic ProphylaxisAntibiotic TherapyArthralgiaAntibiotic TherapyBacterial InfectionBlepharitisBlepharitisCataractCataract OperationConjunctivitisConjunctivitis AllergicConjunctivitis BacterialConjunctivitis InfectiveCorneal Abrasion

Showing 15 of 86 indications

Besifloxacin brand names and reporting trend

Besifloxacin is sold under the brand name Besivance.

Brand names

Besivance104

Quarterly reports (20082025)

2010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking besifloxacin with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.