OpenClaim

Benzyl Side Effects

The most commonly reported side effects of benzyl include toxicity to various agents, diarrhoea, and fatigue, based on 302 FDA adverse event reports from 2004 to 2025. 8.6% of reports found the drug to be ineffective.

Benzyl side effects

Percentages show how often each reaction appears relative to total reports for benzyl.

1
Toxicity To Various Agents10.3%31
2
Drug Ineffective8.6%26
3
Drug Ineffective6.3%19
4
Diarrhoea6.3%19
5
Fatigue6.3%19
6
Nausea5.6%17
7
Rash5.3%16
8
Drug Administered To Patient Of Inappropriate Age5.3%16
9
Off Label Use5.3%16
10
Arthralgia5.0%15
11
Pain5.0%15
12
Headache4.6%14
13
Weight Decreased4.6%14
14
Vomiting4.0%12
15
Dizziness4.0%12

These are voluntary reports and do not establish that benzyl caused these reactions.

Report severity

73.2%Serious221 reports
34.1%Hospitalizations103 reports
17.2%Fatal52 reports

Seriousness is determined by the reporter, not by OpenClaim.

Benzyl drug interactions

Other drugs that appear in adverse event reports alongside benzyl. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-chloride6.3%19
2
Pregabalin6.0%18
3
Adalimumab5.6%17
4
Alprazolam5.6%17
5
Ampicillin5.0%15
6
Ivermectin4.6%14
7
Tramadol-hydrochloride4.6%14
8
Methotrexate4.6%14
9
Acetaminophen4.3%13
10
Etanercept4.3%13
11
Cetirizine-hydrochloride3.6%11
12
Olanzapine3.3%10
13
Heparin3.3%10
14
Hydromorphone-hydrochloride3.3%10
15
Pseudoephedrine3.3%10

Taken alongside

1
Acetaminophen12.9%39
2
Ergocalciferol10.3%31
3
Omeprazole8.9%27
4
Levothyroxine-sodium8.3%25
5
Hydrocortisone7.0%21
6
Fluticasone6.3%19
7
Folic-acid6.0%18
8
Amoxicillin6.0%18
9
Prednisone6.0%18
10
Dexamethasone5.6%17
11
Lansoprazole5.6%17
12
Albuterol5.3%16
13
Aspirin5.3%16
14
Calcium-carbonate5.0%15
15
Diclofenac5.0%15

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports benzyl side effects

55.6% of benzyl adverse event reports involve female patients and 28.8% involve male patients. The largest age group is adult at 41%. These figures reflect who reports side effects, not underlying risk.

Sex

Female55.6%
Male28.8%
Unknown15.6%

Age group

< 29.7%
2–1113.5%
12–175.1%
18–6441.4%
65+30.4%

What is benzyl used for

Conditions and purposes for which patients were taking benzyl when the adverse event was reported.

AcarodermatitisAdverse EventAnaesthetic PremedicationAcarodermatitisBlisterCatheter ManagementCoughDermatosisDepressionEczemaEpidural InjectionExposure Via Breast MilkFungal InfectionHaemorrhoidsHormone Replacement Therapy

Showing 15 of 38 indications

Benzyl brand names and reporting trend

Benzyl is sold under brand names including Ulesfia, Benzyl Benzoate.

Brand names

Ulesfia163
Benzyl Benzoate104

Quarterly reports (20042025)

20052010201520202025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking benzyl with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.