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Benzphetamine Side Effects

The most commonly reported side effects of benzphetamine include drug screen positive, loss of consciousness, and depression, based on 67 FDA adverse event reports from 2004 to 2025. 11.9% of reports found the drug to be ineffective.

Benzphetamine side effects

Percentages show how often each reaction appears relative to total reports for benzphetamine.

1
Drug Ineffective11.9%8
2
Drug Screen Positive7.5%5
3
Loss Of Consciousness6.0%4
4
Depression6.0%4
5
Chronic Kidney Disease6.0%4
6
Dizziness4.5%3
7
Hyperthyroidism4.5%3
8
Vision Blurred4.5%3
9
Blood Cholesterol Increased4.5%3
10
Hypothyroidism4.5%3
11
Constipation4.5%3
12
Drug Ineffective4.5%3
13
Nausea4.5%3
14
Malaise4.5%3
15
Pyrexia4.5%3

These are voluntary reports and do not establish that benzphetamine caused these reactions.

Report severity

49.3%Serious33 reports
25.4%Hospitalizations17 reports
1.5%Fatal1 reports

Seriousness is determined by the reporter, not by OpenClaim.

Benzphetamine drug interactions

Other drugs that appear in adverse event reports alongside benzphetamine. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Sodium-oxybate7.5%5
2
Acetaminophen4.5%3
3
Dextroamphetamine4.5%3
4
Dasatinib4.5%3
5
Esomeprazole4.5%3
6
Omeprazole4.5%3
7
Lansoprazole4.5%3
8
Rofecoxib3.0%2
9
Amphetamine3.0%2
10
Oxycodone3.0%2
11
Methylphenidate3.0%2
12
Hydrocodone3.0%2
13
Pantoprazole-sodium3.0%2
14
Magnesium-hydroxide3.0%2
15
Sodium-bicarbonate3.0%2

Taken alongside

1
Acetaminophen14.9%10
2
Levothyroxine-sodium9.0%6
3
Zolpidem-tartrate9.0%6
4
Hydrocodone9.0%6
5
Nitrofurantoin9.0%6
6
Aspirin7.5%5
7
Lorazepam7.5%5
8
Phentermine7.5%5
9
Oxycodone7.5%5
10
Doxycycline7.5%5
11
Diazepam7.5%5
12
Alprazolam7.5%5
13
Tramadol-hydrochloride7.5%5
14
Gabapentin7.5%5
15
Clonidine6.0%4

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports benzphetamine side effects

68.7% of benzphetamine adverse event reports involve female patients and 19.4% involve male patients. The largest age group is adult at 89%. These figures reflect who reports side effects, not underlying risk.

Sex

Female68.7%
Male19.4%
Unknown11.9%

Age group

< 20.0%
2–110.0%
12–170.0%
18–6489.3%
65+10.7%

What is benzphetamine used for

Conditions and purposes for which patients were taking benzphetamine when the adverse event was reported.

Appetite DisorderAttention Deficit/hyperactivity DisorderDecreased AppetiteDepressionDecreased AppetiteHyperphagiaIncreased AppetiteMedical DietMyasthenia GravisObesityOral HerpesProduct Used For Unknown IndicationProphylaxisWeight AbnormalWeight Control

Showing 15 of 18 indications

Benzphetamine brand names and reporting trend

Quarterly reports (20042025)

2005201020152025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking benzphetamine with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.