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Benralizumab Side Effects

The most commonly reported side effects of benralizumab include asthma, dyspnoea, and death, based on 17,698 FDA adverse event reports from 2017 to 2025. 8.0% of reports found the drug to be ineffective.

Benralizumab side effects

Percentages show how often each reaction appears relative to total reports for benralizumab.

1
Asthma15.7%2,778
2
Dyspnoea10.2%1,802
3
Death8.1%1,438
4
Drug Ineffective8.0%1,418
5
Cough5.3%945
6
Headache4.9%874
7
Product Dose Omission Issue4.7%825
8
Pneumonia4.7%824
9
Wheezing3.9%692
10
Fatigue3.3%592
11
Malaise3.2%566
12
Inappropriate Schedule Of Product Administration3.0%536
13
Arthralgia2.9%516
14
Pyrexia2.9%511
15
Rash2.8%487

These are voluntary reports and do not establish that benralizumab caused these reactions.

Report severity

62.4%Serious11,038 reports
23.4%Hospitalizations4,137 reports
9.9%Fatal1,750 reports

Seriousness is determined by the reporter, not by OpenClaim.

Benralizumab drug interactions

Other drugs that appear in adverse event reports alongside benralizumab. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Budesonide4.2%745
2
Dupilumab3.8%674
3
Formoterol3.5%627
4
Prednisone1.7%303
5
Mepolizumab1.6%286
6
Albuterol1.4%256
7
Omalizumab1.3%229
8
Tiotropium-bromide1.2%208
9
Tezepelumab-ekko1.1%198
10
Montelukast-sodium1.1%194
11
Fluticasone1.0%177
12
Omeprazole0.8%138
13
Ciclesonide0.7%128
14
Glycopyrrolate0.6%98
15
Rosuvastatin0.5%89

Taken alongside

1
Albuterol14.7%2,595
2
Montelukast-sodium9.5%1,675
3
Fluticasone9.4%1,670
4
Prednisone8.3%1,465
5
Tiotropium-bromide7.5%1,321
6
Budesonide7.0%1,246
7
Formoterol6.5%1,150
8
Vilanterol-trifenatate4.2%745
9
Salmeterol-xinafoate3.2%563
10
Umeclidinium-bromide2.9%514
11
Ipratropium-bromide2.5%437
12
Ergocalciferol2.3%399
13
Atorvastatin-calcium2.1%375
14
Levothyroxine-sodium2.0%355
15
Acetaminophen2.0%350

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports benralizumab side effects

62.4% of benralizumab adverse event reports involve female patients and 27.2% involve male patients. The largest age group is adult at 58%. These figures reflect who reports side effects, not underlying risk.

Sex

Female62.4%
Male27.2%
Unknown10.4%

Age group

< 20.1%
2–110.2%
12–171.3%
18–6458.2%
65+40.1%

What is benralizumab used for

Conditions and purposes for which patients were taking benralizumab when the adverse event was reported.

Acute Respiratory Distress SyndromeAllergic EosinophiliaAlpha-1 Antitrypsin DeficiencyAnaphylactic ReactionAspirin-exacerbated Respiratory DiseaseAstheniaAsthmaAsthma Late OnsetAsthma ProphylaxisAsthma-chronic Obstructive Pulmonary Disease Overlap SyndromeAtrial FibrillationAcromegalyAdverse Drug ReactionAdverse EventAnaemia

Showing 15 of 221 indications

Benralizumab brand names and reporting trend

Benralizumab is sold under the brand name Fasenra.

Brand names

Fasenra4,087

Quarterly reports (20172025)

20182020202220242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking benralizumab with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.