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Belinostat Side Effects

The most commonly reported side effects of belinostat include disease progression, nausea, and vomiting, based on 337 FDA adverse event reports from 2011 to 2025.

Belinostat side effects

Percentages show how often each reaction appears relative to total reports for belinostat.

1
Disease Progression20.2%68
2
Nausea16.0%54
3
Vomiting11.9%40
4
Death11.9%40
5
Anaemia11.9%40
6
Dyspnoea10.1%34
7
Fatigue8.9%30
8
Platelet Count Decreased8.6%29
9
Constipation7.4%25
10
Neutrophil Count Decreased6.5%22
11
White Blood Cell Count Decreased6.5%22
12
Diarrhoea5.9%20
13
Pneumonia5.9%20
14
Neutropenia5.9%20
15
Pain5.9%20

These are voluntary reports and do not establish that belinostat caused these reactions.

Report severity

87.8%Serious296 reports
42.7%Hospitalizations144 reports
32.9%Fatal111 reports

Seriousness is determined by the reporter, not by OpenClaim.

Belinostat drug interactions

Other drugs that appear in adverse event reports alongside belinostat. Drugs flagged as a suspected cause appear in the first column. Drugs taken at the same time but not suspected appear in the second.

Also suspected

1
Cyclophosphamide8.0%27
2
Prednisone6.8%23
3
Vincristine-sulfate6.8%23
4
Doxorubicin-hydrochloride6.2%21
5
Ribociclib4.5%15
6
Talazoparib-tosylate3.6%12
7
Tazemetostat-hydrobromide3.3%11
8
Decitabine2.7%9
9
Pralatrexate2.1%7
10
Binimetinib2.1%7
11
Cisplatin1.8%6
12
Epirubicin-hydrochloride1.8%6
13
Durvalumab1.5%5
14
Carboplatin1.2%4
15
Atazanavir-sulfate1.2%4

Taken alongside

1
Folic-acid7.4%25
2
Omeprazole7.1%24
3
Ondansetron6.5%22
4
Acyclovir6.5%22
5
Acetaminophen6.2%21
6
Allopurinol6.2%21
7
Furosemide5.6%19
8
Prednisone4.7%16
9
Amlodipine4.5%15
10
Lorazepam4.2%14
11
Prochlorperazine3.9%13
12
Gabapentin3.9%13
13
Levothyroxine-sodium3.9%13
14
Pantoprazole-sodium3.9%13
15
Dexamethasone3.6%12

Co-occurrence in adverse event reports does not establish a drug interaction. Patients often take multiple medications, and these lists reflect prescribing patterns rather than causal relationships. Consult a healthcare provider about potential drug interactions.

Who reports belinostat side effects

36.2% of belinostat adverse event reports involve female patients and 51.3% involve male patients. The largest age group is elderly at 49%. These figures reflect who reports side effects, not underlying risk.

Sex

Female36.2%
Male51.3%
Unknown12.5%

Age group

< 20.0%
2–110.8%
12–170.8%
18–6449.0%
65+49.4%

What is belinostat used for

Conditions and purposes for which patients were taking belinostat when the adverse event was reported.

Acute Myeloid LeukaemiaAnaplastic Large-cell LymphomaAngioimmunoblastic T-cell LymphomaAcute Myeloid LeukaemiaAcute Myeloid Leukaemia RefractoryAdenocarcinoma PancreasAdult T-cell Lymphoma/leukaemiaAngioimmunoblastic T-cell LymphomaAngioimmunoblastic T-cell Lymphoma Stage IvB-cell LymphomaBladder CancerBreast CancerBreast Cancer MetastaticChemotherapyChronic Myeloid Leukaemia

Showing 15 of 81 indications

Belinostat brand names and reporting trend

Belinostat is sold under the brand name Beleodaq.

Brand names

Beleodaq495

Quarterly reports (20112025)

20112016202020242025

An upward trend reflects increased FAERS reporting overall, not necessarily increased risk.

Taking belinostat with another medication?

Ask OpenClaim about your specific drug combination. Get a sourced report using FDA data, drug labels, and medical literature.